doi: 10.1530/acta.0.1080061.
Development of thyroid autoimmunity
- PMID: 3969811
- DOI: 10.1530/acta.0.1080061
Item in Clipboard
Development of thyroid autoimmunity
Acta Endocrinol (Copenh).
1985 Jan.
Abstract
Two blood samples were taken at an interval of 5 years in a continuing epidemiological study of a rural population in south-western Finland with an age range of 40-64 years at commencement. Paired sera of 680 subjects were tested for antibodies against thyroglobulin and thyroid microsomal antigen. In the seroconversion cases the titres in the second specimens were either low or medium but never high. In the cases selected on the basis of the highest titres in the follow-up specimens, the titres in the baseline specimens were either high or medium but never low. These findings suggest that the emergence and the development of thyroid autoimmune seroreactions are slow processes.
Similar articles
-
Thyroid autoimmunity in siblings: a population study.Acta Endocrinol Suppl (Copenh). 1983;251:11-5. Acta Endocrinol Suppl (Copenh). 1983. PMID: 6573098
-
[Incidence of thyroglobulin and microsomal antibodies in normal subjects (author's transl)].Nihon Naibunpi Gakkai Zasshi. 1975 Feb 20;51(2):98-102. doi: 10.1507/endocrine1927.51.2_98. Nihon Naibunpi Gakkai Zasshi. 1975. PMID: 1171789 Japanese.
-
Serum thyrotrophin and circulating thyroglobulin and thyroid microsomal antibodies in a Finnish population.Acta Endocrinol (Copenh). 1979 Jan;90(1):33-42. doi: 10.1530/acta.0.0900033. Acta Endocrinol (Copenh). 1979. PMID: 760358 No abstract available.
-
[The significance of microsomal antibodies, thyroglobulin antibodies, thyrotropin receptor antibodies in the diagnosis of thyroid diseases].Internist (Berl). 1988 Aug;29(8):538-40. Internist (Berl). 1988. PMID: 3053504 Review. German. No abstract available.
-
[Antigens of normal and pathologically changed human thyroid gland].Sov Med. 1970 Sep;33(9):125-31. Sov Med. 1970. PMID: 4924232 Review. Russian. No abstract available.
Cited by
-
HLA-DR3 and HLA-DR5 confer risk for autoantibody positivity against the thyroperoxidase (mic-TPO) antigen in healthy blood donors.Clin Investig. 1993 Mar;71(3):221-5. doi: 10.1007/BF00180105. Clin Investig. 1993. PMID: 8481624
-
Primary hypothyroidism due to leukemic infiltration of the thyroid gland.J Endocrinol Invest. 1988 Jan;11(1):43-5. doi: 10.1007/BF03350094. J Endocrinol Invest. 1988. PMID: 3162927