Single-Eye Gene Therapy for Leber Hereditary Optic Neuropathy

Hendrik P N Scholl^{1

2}, Bence György^{3

4}

Affiliations

¹ Department of Clinical Pharmacology, Medical University of Vienna, Vienna, Austria.
² European Vision Institute, Basel, Switzerland.
³ Institute of Molecular and Clinical Ophthalmology Basel, Basel, Switzerland.
⁴ Department of Ophthalmology, University of Basel, Basel, Switzerland.

Hendrik P N Scholl et al. JAMA Ophthalmol. 2025.

. 2025 Feb 1;143(2):108-109.

doi: 10.1001/jamaophthalmol.2024.5618.

Hendrik P N Scholl^{1

2}, Bence György^{3

4}

¹ Department of Clinical Pharmacology, Medical University of Vienna, Vienna, Austria.
² European Vision Institute, Basel, Switzerland.
³ Institute of Molecular and Clinical Ophthalmology Basel, Basel, Switzerland.
⁴ Department of Ophthalmology, University of Basel, Basel, Switzerland.

No abstract available

Comment in

Five-Year Outcomes of Lenadogene Nolparvovec Gene Therapy in Leber Hereditary Optic Neuropathy.
Yu-Wai-Man P, Newman NJ, Biousse V, Carelli V, Moster ML, Vignal-Clermont C, Klopstock T, Sadun AA, Sergott RC, Hage R, Degli Esposti S, La Morgia C, Priglinger C, Karanja R, Taiel M, Sahel JA; LHON Study Group. Yu-Wai-Man P, et al. JAMA Ophthalmol. 2025 Feb 1;143(2):99-108. doi: 10.1001/jamaophthalmol.2024.5375. JAMA Ophthalmol. 2025. PMID: 39699886 Free PMC article. Clinical Trial.