[Expert consensus in clinical application of Bailemian Capsules in treatment of insomnia]

Abstract

Bailemian Capsules, as a proprietary Chinese medicine suitable for insomnia of Yin deficiency and fire-excess type, is currently widely used in psychosomatic diseases such as short-term insomnia, chronic insomnia, post-stroke insomnia, and insomnia with anxiety and depression, and it has been recommended by a number of consensus/guidelines/paths. Based on expert interviews, questionnaire surveys, and a systematic review of research literature related to Bailemian Capsules, this paper followed the "evidence-based, consensus-oriented, and experience-reliant" principle and fully combined expert experience and patient preferences on the basis of the best available evidence. According to the characteristics of Bailemian Capsules and the actual clinical situation, 7 recommendations and 12 consensuses were made for the treatment of insomnia, chronic insomnia with anxiety and depression, and insomnia of special populations with Bailemian Capsules alone and combined drugs. During the drafting of the consensus, online and offline opinions were solicited, and peer reviews were collected nationwide. This consensus is applicable to doctors of traditional Chinese medicine(TCM), western medicine, and integrated Chinese and western medicine in hospitals at all levels, as well as clinicians in grassroots health service institutions, providing guidance and reference for the rational use of Bailemian Capsules. It aims to guide and standardize the reasonable use of Bailemian Capsules by clinicians and improve clinical efficacy and safety. The consensus has passed the review of the China Association of Chinese Medicine and has been published, numbered GS/CACM 329-2023.

Keywords: Bailemian Capsules; evidence-based medicine; expert consensus; insomnia; traditional Chinese medicine.