Pathogen-responsive alternative splicing in plant immunity

Abstract

Plant immunity involves a complex and finely tuned response to a wide variety of pathogens. Alternative splicing, a post-transcriptional mechanism that generates multiple transcripts from a single gene, enhances both the versatility and effectiveness of the plant immune system. Pathogen infection induces alternative splicing in numerous plant genes involved in the two primary layers of pathogen recognition: pattern-triggered immunity (PTI) and effector-triggered immunity (ETI). However, the mechanisms underlying pathogen-responsive alternative splicing are just beginning to be understood. In this article, we review recent findings demonstrating that the interaction between pathogen elicitors and plant receptors modulates the phosphorylation status of splicing factors, altering their function, and that pathogen effectors target components of the host spliceosome, controlling the splicing of plant immunity-related genes.

Keywords: biotic stress; effector-triggered immunity (ETI); pattern-triggered immunity (PTI); pre-mRNA splicing; splicing factors.