Is the impact of spontaneous movements on early visual cortex species specific?

Abstract

Recent studies in non-human primates do not find pronounced signals related to the animal's own body movements in the responses of neurons in the visual cortex. This is notable because such pronounced signals have been widely observed in the visual cortex of mice. Here, we discuss factors that may contribute to the differences observed between species, such as state, slow neural drift, eccentricity, and changes in retinal input. The interpretation of movement-related signals in the visual cortex also exemplifies the challenge of identifying the sources of correlated variables. Dissecting these sources is central for understanding the functional roles of movement-related signals. We suggest a functional classification of the possible sources, aimed at facilitating cross-species comparative approaches to studying the neural mechanisms of vision during natural behavior.

Keywords: active vision; behavioral state; comparative neuroscience; macaque; marmoset; mouse.