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Review
. 2025 Mar;39(1):93-119.
doi: 10.1016/j.idc.2024.11.007. Epub 2024 Dec 20.

Invasive Candidiasis

Julia A Schroeder  1 , Cameron M Wilson  1 , Peter G Pappas  2
Affiliations
Review

Invasive Candidiasis

Julia A Schroeder et al. Infect Dis Clin North Am. 2025 Mar.

Abstract

Invasive candidiasis (IC) is a term that refers to a group of infectious syndromes caused by a variety of Candida species, 6 of which cause the vast majority of cases globally. Candidemia is probably the most commonly recognized syndrome associated with IC; however, Candida species can cause invasive infection of any organ, especially visceral organs, vasculature, bones and joints, eyes, and central nervous system. The optimal use of these newer diagnostics coupled with a thoughtful clinical assessment of at-risk patients and the judicious use of effective antifungal therapy is a key to achieving good antifungal stewardship and improved patient outcomes.

Keywords: Antifungals; Bloodstream infection; Candida; Fungal infection; Invasive candidiasis.

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Conflict of interest statement

Disclosure PGP receives research funding from the CDC, Melinta, F2G, Basilea, Scynexis; serves on scientific advisory panels for Basilea, Melinta, F2G, Scynexis, GSK. No equities or speaker bureaus. JAS and CMW have no disclosures.

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