Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2025 Mar;39(1):199-219.
doi: 10.1016/j.idc.2024.11.011. Epub 2024 Dec 21.

Cryptococcosis

Aditi Jani  1 , Ashleigh N Reigler  2 , Sixto M Leal Jr  2 , Todd P McCarty  3
Affiliations
Review

Cryptococcosis

Aditi Jani et al. Infect Dis Clin North Am. 2025 Mar.

Abstract

Cryptococcosis is an invasive fungal infection caused by yeasts of the genus Cryptococcus that causes a significant global burden of disease in both immunocompromised and immunocompetent individuals. Over the past several decades, diagnosis and management of cryptococcal disease have moved to focus on rapid, reliable, and cost-effective care delivery, with the advent of new antigen detection assays and novel antifungal treatment strategies.

Keywords: Cryptococcosis; Fungal disease; HIV; Transplant.

PubMed Disclaimer

Conflict of interest statement

Disclosure T.P. McCarty reports the following disclosures—Consulting: Pfizer; Research Contracts: F2G, Cidara, Basilea, Mundipharma, Scynexis. A. Jani reports no disclosures.

Similar articles

  • Cryptococcosis.
    Maziarz EK, Perfect JR. Maziarz EK, et al. Infect Dis Clin North Am. 2016 Mar;30(1):179-206. doi: 10.1016/j.idc.2015.10.006. Infect Dis Clin North Am. 2016. PMID: 26897067 Free PMC article. Review.
  • Cryptococcosis.
    Kushima H, Ishii H. Kushima H, et al. Med Mycol J. 2025;66(1):27-31. doi: 10.3314/mmj.25.001. Med Mycol J. 2025. PMID: 40024791 Review.
  • Pulmonary cryptococcosis.
    Brizendine KD, Baddley JW, Pappas PG. Brizendine KD, et al. Semin Respir Crit Care Med. 2011 Dec;32(6):727-34. doi: 10.1055/s-0031-1295720. Epub 2011 Dec 13. Semin Respir Crit Care Med. 2011. PMID: 22167400 Review.
  • Cryptococcosis.
    Gushiken AC, Saharia KK, Baddley JW. Gushiken AC, et al. Infect Dis Clin North Am. 2021 Jun;35(2):493-514. doi: 10.1016/j.idc.2021.03.012. Infect Dis Clin North Am. 2021. PMID: 34016288 Review.
  • Epidemiological, Clinical and Outcome Aspects of Patients with Cryptococcosis Caused by Cryptococcus gattii from a Non-endemic Area of Brazil.
    Damasceno-Escoura AH, de Souza ML, de Oliveira Nunes F, Pardi TC, Gazotto FC, Florentino DH, Mora DJ, Silva-Vergara ML. Damasceno-Escoura AH, et al. Mycopathologia. 2019 Feb;184(1):65-71. doi: 10.1007/s11046-018-0304-3. Epub 2018 Nov 10. Mycopathologia. 2019. PMID: 30415450
See all similar articles

Cited by

Substances