Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2025 Mar;17(3):790-800.
doi: 10.1111/os.14329. Epub 2024 Dec 23.

Effectiveness of Total Hip Arthroplasty Combined With Hip Braces for Hip Charcot Arthropathy

Long-Teng Chao  1 , Teng-Feng Zhuang  1 , Song-Wei Huan  1 , Si-Min Luo  1 , Chong-Jie Wu  1 , Wen-Rui Wu  1 , Zhen-Gang Zha  1 , Huan-Tian Zhang  1 , Ning Liu  1
Affiliations

Effectiveness of Total Hip Arthroplasty Combined With Hip Braces for Hip Charcot Arthropathy

Long-Teng Chao et al. Orthop Surg. 2025 Mar.

Abstract

Objective: Charcot arthropathy is characterized by varying degrees of sensory loss and rapidly progressive joint destruction. Historically, limited studies indicated that Charcot arthropathy of the hip joint may be a contraindication for total hip arthroplasty (THA). Yet, some recent studies have shown that good clinical results and acceptable survival rate. Hence, this study aimed to investigate clinical outcomes, radiographic outcomes, complication rates and survivorship of primary THA in Charcot arthropathy.

Methods: We retrospectively included 11 patients (11 hips) with Charcot arthropathy who underwent THA between 1998 and 2016. All involved patients were diagnosed as syphilis. All patients had classic radiographic findings of Charcot arthropathy. The hip braces were used in all patients for six weeks after surgery. Outcome measures included VAS, Oxford Hip Score, and UCLA score. Statistical analyses involved t-tests, chi-square tests, and Kaplan-Meier survival analysis.

Results: The average follow-up period was 81.73 months. The average VAS, Oxford Hip Score, and UCLA score were improved significantly. There was higher complication rate of 45.5% after THA. Reoperation was carried out in two patients due to dislocation and acetabular component loosening. The Kaplan-Meier survivorship with an end point of reoperation for any reason was 81.8%.

Conclusions: THA is proved to be reasonable in improving hip joint function, which is suitable for patients with Charcot hip joint. Although the complication rate is high, we consider that THA combined with hip brace may be a valid treatment choice for Charcot arthropathy with detailed preoperative planning and proper precautions.

Keywords: Charcot arthropathy; complications; hip brace; instability; survivorship; total hip arthroplasty.

PubMed Disclaimer

Conflict of interest statement

The authors declare no conflicts of interest.

Figures

FIGURE 1
FIGURE 1
Clinical outcomes.
FIGURE 2
FIGURE 2
(A) An anteroposterior radiograph and (B) a lateral radiograph of a 64‐year‐old woman with Charcot arthropathy of right hip joint. (C) Posterior dislocation following installment of antibiotic‐loaded cement spacer. (D) The patient accepted a THA with a tantalum augment for a Paprosky type 2B acetabular bone defect.
FIGURE 3
FIGURE 3
(A) An anteroposterior radiograph and (B) a lateral radiograph of a 71‐year‐old woman with Charcot arthropathy of right hip joint. (C) The patient occurred intraoperative calcar fracture which were treated with wire cerclage successfully.
FIGURE 4
FIGURE 4
(A) An anteroposterior radiograph and (B) a lateral radiograph of a 62‐year‐old man with Charcot arthropathy of right hip joint. (C) He occurred intraoperative calcar fracture which were treated with wire cerclage successfully.
FIGURE 5
FIGURE 5
(A) An anteroposterior radiograph of 70‐year‐old man with Charcot arthropathy of right hip joint. (B) The patient occurred aseptic acetabular component loosening. (C) He underwent revision of THA with metal augment and new acetabular component. No recurrence of loosening until the most recent follow‐up.
FIGURE 6
FIGURE 6
Kaplan–Meier survival analysis for any reoperation.
See this image and copyright information in PMC

References

    1. Gupta R., “A Short History of Neuropathic Arthropathy,” Clinical Orthopaedics and Related Research 296 (1993): 43–49. - PubMed
    1. Inoue D., Kabata T., Kajino Y., et al., “Clinical Results of Total Hip Arthroplasty in Two Patients With Charcot Hip Joints due to Congenital Insensivity to Pain With Anhydrosis,” Case Reports in Orthopedics 2018 (2018): 1–5. - PMC - PubMed
    1. Sudanese A., Giardina F., Biondi F., Traina F., Bertoni F., and Toni A., “Charcot's Joint Secondary to Neurologic Complications of Epidural Anaesthesia: A Case Report,” La Chirurgia Degli Organi di Movimento 91 (2008): 159–162. - PubMed
    1. Rąpała K. and Obrębski M., “Charcot's Arthropathy of the Hip Joints: A Late Manifestation of Tabes Dorsalis Successfully Treated by Total Joint Arthroplasty. Report of 2 Cases,” Journal of Arthroplasty 22, no. 5 (2007): 771–774. - PubMed
    1. Tibbo M. E., Chalmers B. P., Berry D. J., Pagnano M. W., Lewallen D. G., and Abdel M. P., “Primary Total Knee Arthroplasty in Patients With Neuropathic (Charcot) Arthropathy: Contemporary Results,” Journal of Arthroplasty 33, no. 9 (2018): 2815–2820. - PubMed