doi: 10.1016/0006-8993(85)91403-9.
Subclasses of olfactory receptor cells and their segregated central projections demonstrated by a monoclonal antibody
- PMID: 3971146
- DOI: 10.1016/0006-8993(85)91403-9
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Subclasses of olfactory receptor cells and their segregated central projections demonstrated by a monoclonal antibody
Brain Res.
.
Abstract
A library of monoclonal antibodies (MAbs) was generated against a homogenate of the rabbit olfactory bulb. One of them immunohistochemically distinguished a subgroup of olfactory nerves. Both in the olfactory bulb and the epithelium, this MAb labeled most olfactory receptor axons in the lateral but only a small fraction in the medial portion. These findings demonstrate a molecular heterogeneity among olfactory receptor cells and suggest a functional division between the lateral and the medial portions of the epithelium and the bulb.
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