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. 1985 Feb 4;326(1):192-6.
doi: 10.1016/0006-8993(85)91403-9.

Subclasses of olfactory receptor cells and their segregated central projections demonstrated by a monoclonal antibody

S C Fujita, K Mori, K Imamura, K Obata

Subclasses of olfactory receptor cells and their segregated central projections demonstrated by a monoclonal antibody

S C Fujita et al. Brain Res. .

Abstract

A library of monoclonal antibodies (MAbs) was generated against a homogenate of the rabbit olfactory bulb. One of them immunohistochemically distinguished a subgroup of olfactory nerves. Both in the olfactory bulb and the epithelium, this MAb labeled most olfactory receptor axons in the lateral but only a small fraction in the medial portion. These findings demonstrate a molecular heterogeneity among olfactory receptor cells and suggest a functional division between the lateral and the medial portions of the epithelium and the bulb.

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