Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2024 Jan 29;59(6):e815-e820.
doi: 10.1055/s-0043-1771483. eCollection 2024 Dec.

Update on Conventional Osteosarcoma

Luiz Eduardo Moreira Teixeira  1 , Alex Guedes  2 , Suely Akiko Nakagawa  3 , Karine Corrêa Fonseca  4 , Eduardo Ribeiro Lima  4
Affiliations

Update on Conventional Osteosarcoma

Luiz Eduardo Moreira Teixeira et al. Rev Bras Ortop (Sao Paulo). .

Abstract

Conventional osteosarcoma is a high-grade malignant tumor characterized by the production of osteoid matrix by malignant osteoblasts. It typically affects the long bones of children and adolescents. Treatment includes systemic chemotherapy and a local surgical approach with wide resection. Recent advances in oncology concepts, imaging, surgical planning, and cancer treatment protocols allow for improved survival and a higher limb preservation rate. This paper addresses the current status regarding the incidence, pathology, treatment, and prognosis of conventional high-grade osteosarcoma.

Keywords: neoplasms; ostesarcoma; sarcoma.

PubMed Disclaimer

Conflict of interest statement

Conflito de Interesses Os autores declaram não haver conflito de interesses.

Figures

Fig. 1
Fig. 1
Malignant osteoblasts producing osteoid matrix. Source: Author's personal file.
Fig. 2
Fig. 2
Radiographic appearance of conventional osteosarcoma. Source: Author's personal file.
Fig. 3
Fig. 3
Reconstruction with non-conventional distal femur endoprosthesis. Source: Author's personal file.
Fig. 1
Fig. 1
Osteoblastos malignos produzindo matriz osteóide. Fonte Arquivo pessoal do autor.
Fig. 2
Fig. 2
Aspecto radiográfico do osteosarcoma convencional. Fonte arquivo pessoal do autor.
Fig. 3
Fig. 3
Reconstrução com endoprótese não convencional de femur distal. Fonte arquivo pessoal do autor.
See this image and copyright information in PMC

Similar articles

See all similar articles

Cited by

References

    1. Flanagan A M, Blay J Y, Bovée J VMG . Lyon, France: International Agency for Research on Cancer; 2020. Bone tumours: Introduction; pp. 340–444.
    1. Baumhoer D, Böhling T O, Cates J MM . Lyon, France: International Agency for Research on Cancer; 2020. Osteosarcoma; pp. 403–409.
    1. Cole S, Gianferante D M, Zhu B, Mirabello L. Osteosarcoma: A Surveillance, Epidemiology, and End Results program-based analysis from 1975 to 2017. Cancer. 2022;128(11):2107–2118. - PMC - PubMed
    1. Mansur S F, Barbosa C SP, Miranda D et al.Sarcoma osteogênico - Estudo retrospectivo epidemiológico de 184 casos diagnosticados em Belo Horizonte, Minas Gerais. Rev Bras Ortop. 1996;31(12):995–1000.
    1. Castro H C, Ribeiro K CB, Bruniera P. Osteossarcoma: Experiência do Serviço de Oncologia Pediátrica da Santa Casa de Misericórdia de São Paulo. Rev Bras Ortop. 2008;43(04):108–115.

LinkOut - more resources