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. 2024 Nov 21;16(11):e74192.
doi: 10.7759/cureus.74192. eCollection 2024 Nov.

Diagnosis and Treatment of Spondylodiscitis: Insights From a Five-Year Single-Center Study

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Diagnosis and Treatment of Spondylodiscitis: Insights From a Five-Year Single-Center Study

Diana Lima et al. Cureus. .

Abstract

Introduction: Spondylodiscitis is a rare but increasingly infectious disease affecting the intervertebral discs and vertebrae.

Methods: This study retrospectively analyzed 36 patients admitted with spondylodiscitis over a five-year period, examining demographics, clinical features, risk factors, causative agents, treatment approaches, and outcomes.

Results: The patient cohort had a mean age of 53.7 years, with a slight male predominance (55.6%, n=20). The most common symptoms were pain corresponding to 83.3% (n=30) followed by fever in 44.4% (n=16), and neurological symptoms were observed in 41.7% (n=15) of cases. The lumbar spine was the most frequently affected region (47.2%, n=17), and abscess formation, particularly involving the psoas muscle, occurred in 37.5% of cases. Notably, Mycobacterium tuberculosis was the predominant causative agent representing 50% (n=18) of all cases. All patients received antibiotic treatment, and 47.2% (n=17) required additional surgical intervention. Rehabilitation was initiated during hospitalization for 86.1% (n=31) of patients with six patients transferred to a rehabilitation yard. The overall mortality rate was 11.1% (n=3), primarily due to septic shock.

Conclusion: This study underscores the challenges of diagnosing spondylodiscitis and highlights the importance of a multidisciplinary approach to management, involving early rehabilitation to improve functional outcomes.

Keywords: lumbar abscess; rehabilitation; spinal cord infection; spine surgery; spondylodiscitis.

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Conflict of interest statement

Human subjects: Consent for treatment and open access publication was obtained or waived by all participants in this study. Animal subjects: All authors have confirmed that this study did not involve animal subjects or tissue. Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work.

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