Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Randomized Controlled Trial
. 2024 Dec 23;145(1):85.
doi: 10.1007/s00402-024-05639-1.

5-years outcomes following arthroscopic anterior cruciate ligament reconstruction comparing quadruple hamstring and peroneus longus tendon autografts: a randomized control trial

Umer Butt  1   2 , Filip Vuletic  3   4 , M Ali Ahmed Shaikh  1 , Amanullah  1   5 , Ghufran Ur Rehman  1   6 , Imran Ali Shah  1 , Anders Stålman  7   8 , Zainab Aqeel Khan  1   9   10
Affiliations
Randomized Controlled Trial

5-years outcomes following arthroscopic anterior cruciate ligament reconstruction comparing quadruple hamstring and peroneus longus tendon autografts: a randomized control trial

Umer Butt et al. Arch Orthop Trauma Surg. .

Abstract

Aims: This study presents clinical outcomes, functional results, and return to sports after anterior cruciate ligament (ACL) reconstruction using quadruple hamstring tendon autograft or peroneus longus tendon autograft in a randomized controlled trial.

Patients and methods: Between February 2018 and July 2019, patients who underwent ACL reconstruction were randomly assigned to two groups: hamstring and peroneus longus. Patient related outcome measurements and pain intensity were evaluated using IKDC, Lysholm, and visual analog scores at 3 and 6 months, 1, 2, and 5 years after the surgery. At the 5 year follow-up, anterior stability was tested using the 3D printable Knee Arthrometer. In addition, in the peroneus longus group, ankle functional assessment was performed using the American foot and ankle score. Additionally, data on the return to sports/activities was collected for both groups at the last follow-up.

Results: Sixty patients, with 30 in the hamstring group and 30 in the peroneus group, were included in the study. Patients were predominately male and with low activity demands. After five years of follow-up, there was no significant difference in functional assessment scores (IKDC and Lysholm) between the two groups (P n.s). The median graft diameter was 7.9 ± 0.4 mm in the hamstring tendon group and 8.9 ± 0.2 mm in the PL group (P < 0.001). The improvement in Arthrometer testing measurements (AMT) for the operated knees in the hamstring and peroneus longus groups were similar. In the peroneus longus group, the mean postoperative foot and ankle score was 98.6 ± 3.9 (range = 85-100).

Conclusion: Using Peroneus longus tendon autograft for arthroscopic ACL reconstruction is a feasible alternative as studied in this cohort of predominately male patients with low activity demands. The graft diameter in this study was sufficient, and the results regarding laxity and patient related outcome measurements were similar to those achieved with hamstring tendon autografts.

Level of evidence: Level I TRIAL REGISTRATION: ChiCTR2000036989.

Keywords: ACL reconstruction; Autograft; Hamstring autograft; Peroneus longus; Sports injury; Sports surgery.

PubMed Disclaimer

Conflict of interest statement

Declarations. Conflict of interest: The authors have no competing interests to declare that are relevant to the content of this article. Ethical approval: The ethical approval was obtained from United medical and dental college (board (UMDC/Ethics/2016/15/06/391). Patient consent: The informed consent was taken from all patients before enrolment in the study. Clinical trial registration: The trial was registered in the Chinese clinical trial registry with the registration number ChiCTR2000036989.

Figures

Fig. 1
Fig. 1
Flow chart of the study showing participants randomization and enrolment
Fig. 2
Fig. 2
Comparison of functional outcomes (IKDC and Lysholm) between hamstring and PL group at different follow-up (pre-operative, 3,6 months, 1,2- and 5-years post-operative)
See this image and copyright information in PMC

References

    1. Cimino FM, Volk BS, Setter D (2010) Anterior cruciate ligament injury: diagnosis, management, and prevention. Am Fam Physician 82(8):917–922 - PubMed
    1. Shaerf DA, Pastides PS, Sarraf KM, Willis-Owen CA (2014) Anterior cruciate ligament reconstruction best practice: a review of graft choice. World J Orthop 5(1):23 - PMC - PubMed
    1. Schoderbek RJ Jr, Treme GP, Miller MD (2007) Bone-patella tendon-bone autograft anterior cruciate ligament reconstruction. Clin Sports Med 26(4):525–547 - PubMed
    1. Romanini E, D’Angelo F, De Masi S, Adriani E, Magaletti M, Lacorte E, Mele A (2010) Graft selection in arthroscopic anterior cruciate ligament reconstruction. J Orthop Traumatol 11(4):211–219 - PMC - PubMed
    1. Jansson KA, Linko E, Sandelin J, Harilainen A (2003) A prospective randomized study of patellar versus hamstring tendon autografts for anterior cruciate ligament reconstruction. Am J Sports Med 31(1):12–18 - PubMed

Publication types