Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2024 Oct 28:13:103.
doi: 10.4103/abr.abr_408_23. eCollection 2024.

Indications of Amniocentesis and its Early and Late Complications

Payman Rezagholi  1 , Mohammad A Rasouli  2 , Shamsi Zare  3
Affiliations

Indications of Amniocentesis and its Early and Late Complications

Payman Rezagholi et al. Adv Biomed Res. .

Abstract

Background: Currently, it is recommended to arrange screening for all women who are referred for prenatal care before the 20th week of gestation. Congenital and genetic diseases lead to disability and death in 3% of babies. Prenatal diagnosis is the only way to prevent the birth of babies with genetic disorders. This study was conducted with the aim of investigating the indications of amniocentesis as well as its early and late complications.

Materials and methods: This retrospective study was conducted on 216 patients who were referred to the Perinatology Clinic of Sanandaj Besat Hospital in 2019-2020 and were candidates for amniocentesis. After collecting the data, analysis of data was done in SPSS software (version 21).

Results: In the investigation of complications caused by amniocentesis, spontaneous abortion occurred in five cases (2.31%), amniotic fluid leakage in nine cases (4.6%), spotting in seven cases (3.24%), chorioamnionitis in one case (0.46%), and premature birth in 35 cases (16.2%). In this study, there were no reports of skin and eye complications.

Conclusion: Based on the results of this research, the most common early and late complications were amniotic fluid leakage and childbirth before 37 weeks of gestation, respectively.

Keywords: Amniocentesis; complications; early; late.

PubMed Disclaimer

Conflict of interest statement

There are no conflicts of interest.

Similar articles

See all similar articles

Cited by

References

    1. Vink J, Fuchs K, D'alton ME. Amniocentesis in twin pregnancies: A systematic review of the literature. Prenat Diagn. 2012;32:409–16. - PMC - PubMed
    1. Kalogiannidis I, Prapa S, Dagklis T, Karkanaki A, Petousis S, Prapas Y, et al. Amniocentesisrelated adverse outcomes according to placental location and risk factors for fetal loss after midtrimester amniocentesis. Clin Exp Obstet Gynecol. 2011;38:239–42. - PubMed
    1. Cai L, Yang Y, Zou G, Zhang Y, Wu F, Yuan M, et al. Pregnancy loss after amniocentesis with double-needle insertions in twin pregnancies. Twin Res Hum Genet. 2022;25:50–5. - PubMed
    1. Theodora M, Antsaklis A, Antsaklis P, Blanas K, Daskalakis G, Sindos M, et al. Fetal loss following second trimester amniocentesis. Who is at greater risk? How to counsel pregnant women? J Matern Fetal Neonatal Med. 2016;29:590–5. - PubMed
    1. Liu X, Wang J, Luo W, Wang Q, Liu Z, Wang H, et al. The risk factors of procedure-related complications after amniocentesis in twin pregnancies: A retrospective analysis. BMC Pregnancy and Childbirth. 2023;23:587. - PMC - PubMed

LinkOut - more resources