A perspective: neuraxial therapeutics in pain management: now and future
- PMID: 39720319
- PMCID: PMC11666549
- DOI: 10.3389/fpain.2024.1505019
A perspective: neuraxial therapeutics in pain management: now and future
Abstract
The neuraxial delivery of drugs for the management of pain and other spinal pathologies is widely employed and is the subject of a large volume of ongoing research with several thousand papers appearing in the past 5 years alone on neuraxial delivery. Several learned texts have been recently published. A number of considerations have contributed to this widespread interest in the development of the use of neuraxial therapeutics to manage pain. In the following section, major topics relevant to spinal encoding and in the use of neuraxial therapeutics are considered by the Frontiers in Pain Research editors of the research topic: "Neuraxial Therapeutics in Pain Management: Now and Future". This paper seeks to serve as a perspective to encourage the submission of manuscripts reflecting research in this exciting area.
Keywords: neuraxial delivery; neuraxial targets; neuraxial therapeutics; pain management; spinal drug delivery; therapeutic pain intervention.
© 2024 DeAndres, Dickenson, Hayek, Linninger and Yaksh.
Conflict of interest statement
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
Similar articles
-
What's New in Neuraxial Labor Analgesia.Curr Anesthesiol Rep. 2021;11(3):340-347. doi: 10.1007/s40140-021-00453-6. Epub 2021 Aug 27. Curr Anesthesiol Rep. 2021. PMID: 34466127 Free PMC article. Review.
-
Continuous local bupivacaine wound infusion with neuraxial morphine reduces opioid consumption after cesarean delivery.J Matern Fetal Neonatal Med. 2019 Dec;32(23):3895-3902. doi: 10.1080/14767058.2018.1474872. Epub 2018 May 30. J Matern Fetal Neonatal Med. 2019. PMID: 29848107
-
Neuraxial drug delivery in pain management: An overview of past, present, and future.Best Pract Res Clin Anaesthesiol. 2023 Jun;37(2):243-265. doi: 10.1016/j.bpa.2023.04.003. Epub 2023 Apr 14. Best Pract Res Clin Anaesthesiol. 2023. PMID: 37321769 Review.
-
Current and Future Issues in the Development of Spinal Agents for the Management of Pain.Curr Neuropharmacol. 2017;15(2):232-259. doi: 10.2174/1570159x14666160307145542. Curr Neuropharmacol. 2017. PMID: 26861470 Free PMC article. Review.
-
Reducing risk of spinal haematoma from spinal and epidural pain procedures.Scand J Pain. 2018 Apr 25;18(2):129-150. doi: 10.1515/sjpain-2018-0041. Scand J Pain. 2018. PMID: 29794308 Review.
References
-
- Beall DP PM, DePalma MJ, Davis T, Amirdelfan K, Hunter CW, editors. Intrathecal Pump Drug Delivery. Switzerland: Springer Cham; (2022) XIII. p. 194.
-
- Buvanendran ADS, Deer TR. Intrathecal Drug Delivery for Pain and Spasticity. Philadelphia, PA: Saunders; (2012).
-
- Front Matter. In: Chawla PA, Loebenberg R, Dua K, Parikh V, Chawla V, editors. Novel Drug Delivery Systems in the Management of CNS Disorders. Exeter, United Kingdom: Academic Press; (2025). p. iii.
-
- Yaksh THS. Neuraxial Therapeutics: A Comprehensive Guide. Switzerland: Springer Nature; (2023).
LinkOut - more resources
Full Text Sources
Miscellaneous