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Review
. 2020 Oct 13:14:e13.
doi: 10.15420/usc.2020.18. eCollection 2020.

The Role of Hemodynamic Support in High-risk Percutaneous Coronary Intervention

Affiliations
Review

The Role of Hemodynamic Support in High-risk Percutaneous Coronary Intervention

Charles Simonton et al. US Cardiol. .

Abstract

Patients with advanced age, complex coronary anatomy, and multiple comorbidities are often unsuitable for surgical revascularization. In this setting, hemodynamic support devices are used as an adjunct to percutaneous coronary intervention to maintain hemodynamic stability and enable optimal revascularization. This article provides an overview of percutaneous hemodynamic support devices currently used in clinical practice for high-risk percutaneous coronary intervention. These include the intra-aortic balloon pump, centrifugal pumps (TandemHeart, venous arterial extracorporeal membrane oxygenation), and micro-axial Impella pump. The hemodynamic effects, clinical evidence supporting improved outcomes and recovery of heart function, and associated complications with these devices are highlighted, with a special focus on Impella pumps.

Keywords: Impella; Percutaneous coronary intervention; balloon pump; extracorporeal membranous oxygenation; hemodynamic support devices; high-risk percutaneous coronary intervention; percutaneous left ventricular assist devices.

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Conflict of interest statement

Disclosure: CS is a consultant for Abiomed. CT is a consultant for Boston Scientific and Abiomed. JRW is a consultant, proctor, speaker, and advisory board member for Boston Scientific and Abbott Vascular; a consultant, speaker, and advisory board member and has received research support for Abiomed; is on an advisory board for Phillips, and is a proctor for Asahi Intecc. DLM is a consultant and speaker, and has received research support from Abiomed. TGD is a speaker and proctor for Abiomed.

Figures

Figure 1:
Figure 1:. Growing Population of Complex And High-risk Patients Who Could Benefit From Hemodynamic Support
Figure 2:
Figure 2:. Percutaneous Mechanical Circulatory Support Devices Currently Used For High-risk Percutaneous Coronary Intervention

References

    1. Virani SS, Alonso A, Benjamin EJ et al. Heart disease and stroke statistics –2020 update: a report from the American Heart Association. Circulation. 2020;141:e139–596. doi: 10.1161/CIR.0000000000000757. - DOI - PubMed
    1. Cohen DJ, Van Hout B, Serruys PW et al. Quality of life after PCI with drug-eluting stents or coronary-artery bypass surgery. N Engl J Med. 2011;364:1016–26. doi: 10.1056/NEJMoa1001508. - DOI - PubMed
    1. Norris CM, Saunders LD, Ghali WA et al. Health-related quality of life outcomes of patients with coronary artery disease treated with cardiac surgery, percutaneous coronary intervention or medical management. Can J Cardiol. 2004;20:1259–66. - PubMed
    1. Velazquez EJ, Lee KL, Jones RH et al. Coronary-artery bypass surgery in patients with ischemic cardiomyopathy. N Engl J Med. 2016;374:1511–20. doi: 10.1056/NEJMoa1602001. - DOI - PMC - PubMed
    1. Neumann FJ, Sousa-Uva M, Ahlsson A et al. 2018 ESC/EACTS guidelines on myocardial revascularization. Eur Heart J. 2019;40:87–165. doi: 10.1093/eurheartj/ehy394. - DOI - PubMed

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