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. 2024 Dec 11:15:1473599.
doi: 10.3389/fphar.2024.1473599. eCollection 2024.

Bibliometric analysis of nanotechnology in spinal cord injury: current status and emerging frontiers

Affiliations

Bibliometric analysis of nanotechnology in spinal cord injury: current status and emerging frontiers

XiaoPeng Gu et al. Front Pharmacol. .

Abstract

Objective: The objective of this study was to analyze the impact of nanotechnology on the treatment and recovery of spinal cord injury (SCI), a condition that has profound global effects on physical and psychological health.

Methods: We utilized the Web of Science Core Collection to obtain bibliometric data. With the tools such as VOSviewer and CiteSpace, we conducted a comprehensive review of 422 relevant publications to identify research trends and influential works in the field of nanotechnology applied to SCI.

Results: The analysis revealed significant contributions from both China, Sweden and the United States, and pinpointed inflammation, apoptosis, and nano-drug delivery as the primary areas of focus in current research, with emerging trends evident in recent literature.

Conclusion: Nanotechnology hold great potential to revolutionize the treatment of SCI through targeted therapeutics and modulation of pathological processes. This study provided valuable insights into the evolving landscape of SCI research, underscoring the importance of continuous innovation and interdisciplinary collaboration.

Keywords: CiteSpace; bibliometric; inflammation; nanotechnology; spinal cord injury.

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Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Figures

FIGURE 1
FIGURE 1
Publication screening flowchart.
FIGURE 2
FIGURE 2
Annual output of nanotechnology in SCI.
FIGURE 3
FIGURE 3
The visualization of countries on research of nanotechnology in SCI. (A, B) Top 5 countries by number of publications over time (C) Proportion of articles published by the top 10 countries (D).
FIGURE 4
FIGURE 4
The top 10 institutions with the most publications and their cooperative relationships (A, B).
FIGURE 5
FIGURE 5
The visualization of author on research of nanotechnology in SCI (A, B).
FIGURE 6
FIGURE 6
Top 15 subject categories with the strongest citation burst.
FIGURE 7
FIGURE 7
Top 25 keywords with the strongest citation bursts.
FIGURE 8
FIGURE 8
Keyword cluster snapshots. (A) Clustering form. (B) Timeline form.
FIGURE 9
FIGURE 9
Hot spots and frontiers in the field of nanotechnology in SCI research in recent years.

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References

    1. Ahuja C. S., Wilson J. R., Nori S., Kotter M. R. N., Druschel C., Curt A., et al. (2017). Traumatic spinal cord injury. Nat. Rev. Dis. Prim. 3, 17018. 10.1038/nrdp.2017.18 - DOI - PubMed
    1. Alzate-Correa D., Lawrence W. R., Salazar-Puerta A., Higuita-Castro N., Gallego-Perez D. (2022). Nanotechnology-driven cell-based therapies in regenerative medicine. Aaps J. 24 (2), 43. 10.1208/s12248-022-00692-3 - DOI - PMC - PubMed
    1. Bao T., Li N., Chen H., Zhao Z., Fan J., Tao Y., et al. (2023). Drug-loaded zwitterion-based nanomotors for the treatment of spinal cord injury. ACS Appl. Mater Interfaces 15 (27), 32762–32771. 10.1021/acsami.3c05866 - DOI - PubMed
    1. Basso D. M., Beattie M. S., Bresnahan J. C. (1995). A sensitive and reliable locomotor rating scale for open field testing in rats. J. Neurotrauma 12 (1), 1–21. 10.1089/neu.1995.12.1 - DOI - PubMed
    1. Bayda S., Adeel M., Tuccinardi T., Cordani M., Rizzolio F. (2019). The history of nanoscience and nanotechnology: from chemical-physical applications to nanomedicine. Molecules 25 (1), 112. 10.3390/molecules25010112 - DOI - PMC - PubMed

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