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. 1985 Mar;54(3):573-9.

Anaphylactic-like reaction of small intestinal epithelium in parasitized guinea-pigs

D A Russell, G A Castro

Anaphylactic-like reaction of small intestinal epithelium in parasitized guinea-pigs

D A Russell et al. Immunology. 1985 Mar.

Abstract

Antigens derived from Trichinella spiralis were used to challenge, in vitro, sensitized jejunum from infected guinea-pigs while monitoring ion transport properties of the tissue. Antigen challenge resulted in dose-dependent increases in trans-epithelial electrical potential difference and short circuit current. Both antigen-stimulated electrical alterations and Schultz-Dale contractions were demonstrated in small intestinal tissue after the passive transfer of immune serum containing anti-trichinella homocytotropic antibodies.

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