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Case Reports
. 2025 Nov 1;19(6):753-757.
doi: 10.1097/ICB.0000000000001657.

SEROUS RETINAL DETACHMENT DUE TO CRYPTOCOCCOSIS IN AN IMMUNOCOMPETENT PATIENT

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Case Reports

SEROUS RETINAL DETACHMENT DUE TO CRYPTOCOCCOSIS IN AN IMMUNOCOMPETENT PATIENT

Anna Carolina Carvalho Araujo et al. Retin Cases Brief Rep. .

Abstract

Purpose: The objective of this study was to report a case of bilateral ocular cryptococcosis in an immunocompetent patient without neurologic findings.

Methods: This was a case report.

Results: A 30-year-old healthy White man presented with painless blurred vision in the left eye. Examination showed bilateral serous detachments and white retinal lesions. The visual acuity was 20/40 in the right eye and hand motions in the left eye. Neurologic workup and serologies were negative, and a computer tomography-positron emission tomography scan showed diffuse lymph node enlargement with metabolic activity and a suspected lymphoproliferative disorder. The myelogram and immunohistochemistry were normal. A biopsy of the cervical lymph nodes was positive for Cryptococcus neoformans . He was treated with antifungal medications and had complete resolution of the subretinal fluid and visual acuity improvement.

Conclusions: Cryptococcosis is a rare entity in an immunocompetent person. A systemic workup is necessary to diagnose cryptococcosis and initiate prompt treatment.

Keywords: amphotericin B; ocular cryptococcosis; serous detachment.

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References

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    1. Firacative C, Lizarazo J, Illnait-Zaragozi MT, et al. The status of cryptococcosis in Latin America. Mem Inst Oswaldo Cruz 2018;113:e170554.

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