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Case Reports
. 2025 Jan;133(1):e13488.
doi: 10.1111/apm.13488.

Monkeypox virus infection in pregnancy: description of two cases reported to the Colombian National Institute of Health

Mercado-Reyes Marcela  1 , Daza Marcela  1 , Rodríguez Peña Yazmín  2 , Araque Muñoz Paula  3 , Franco-Muñoz Carlos  1 , Ruíz-Moreno Hector  1 , Corchuelo Chavarro Sheryll  1 , Portilla Velandia Claudia  1 , Osorio Usaquén Johana  1 , Ávila Mellizo Greace  1 , Narvaez Díaz Nubia  1 , Walteros Diana  1 , Cortes Palacio Katherinne  4 , Piñeros Daza José Ángel  5
Affiliations
Case Reports

Monkeypox virus infection in pregnancy: description of two cases reported to the Colombian National Institute of Health

Mercado-Reyes Marcela et al. APMIS. 2025 Jan.

Abstract

Monkeypox (mpox), caused by the MPOXV (monkeypox virus), has been endemic in Africa since its first identification in 1958. However, in May 2022, the world witnessed the first global outbreak associated with the West African clade. Even though thousands of cases have been recorded, our understanding of vertical transmission during pregnancy remains restricted due to an absence of reported cases in pregnant women and a lack of adequate clinical descriptions. The cases of two pregnant women, ages 33 and 24, who tested positive for MPOXV at 31 and 13.4 weeks of gestation, respectively, are presented. In all cases, extensive clinical, histological, and molecular examinations of the mothers and neonates revealed no indication of vertical transmission.

Keywords: Monkeypox; Monkeypox virus; Public Health Surveillance; case reports; pregnancy.

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References

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