Thiazole and Isothiazole Chemistry in Crop Protection

Abstract

Thiazole and isothiazole are types of five-membered heterocycles that contain both sulfur and nitrogen atoms. They have gained attention in the field of green pesticide research due to their low toxicity, strong biological activity, and ability to undergo diverse structural modifications. By incorporating thiazole and isothiazole groups into various compounds, researchers have been able to create a wide range of pesticides with broad-spectrum effectiveness. Understanding the relationship between the structure of these compounds and their activities is crucial for the development of new and highly potent pesticides. This review highlights thiazole and isothiazole derivatives with various biological activities and aims to inspire the development of innovative pesticide based on these structures.

Keywords: biological activity; isothiazole derivatives; structure−activity relationship; thiazole derivatives.