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Review
. 2024 Dec 11;10(12):859.
doi: 10.3390/jof10120859.

Cerebrospinal Drain Infection by Candida auris: A Case Report and Review of the Literature

Asimenia Halioti  1 , Charikleia S Vrettou  1 , Eleftherios Neromyliotis  2 , Evdokia Gavrielatou  1 , Aikaterini Sarri  1 , Zoi Psaroudaki  3 , Eleni E Magira  1
Affiliations
Review

Cerebrospinal Drain Infection by Candida auris: A Case Report and Review of the Literature

Asimenia Halioti et al. J Fungi (Basel). .

Abstract

Candida auris is notorious for its ability to spread within healthcare environments, particularly in intensive care units (ICUs), posing significant challenges for clinicians as treatment options become limited. This is especially concerning in the context of central nervous system (CNS)-invasive infections. While rare, its involvement in nosocomial brain ventriculitis presents substantial diagnostic and therapeutic challenges, with no established guidelines for managing CNS infections caused by Candida auris. This report presents a case of Candida auris ventriculitis in an ICU patient and offers a comprehensive and targeted literature review, emphasizing diagnostic approaches, treatment strategies, and the clinical complexities of managing this emerging pathogen in CNS infections.

Keywords: Candida auris; cerebrospinal fluid; external ventricular drain; ventriculitis.

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Conflict of interest statement

The authors declare no conflicts of interest.

Figures

Figure 1
Figure 1
Magnetic resonance imaging scan (A) of the patient revealed contrast enhancement of the walls of the enlarged ventricular system (B) with restricted diffusion, consistent with ventriculitis (C).
Figure 2
Figure 2
Search strategy for the identification of meningitis and ventriculitis cases, caused by Candida auris, until the end of July 2024. CNS: central nervous system.
See this image and copyright information in PMC

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