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Review
. 2025 Apr 1;44(4):405-411.
doi: 10.1097/ICO.0000000000003775. Epub 2024 Dec 19.

Advances in the Diagnosis and Management of Limbal Stem Cell Deficiency

Thanachaporn Kittipibul  1   2 , Chea Piseth Dalin  3 , Ali Masoudi  4 , Jie Zheng  4 , Sophie X Deng  4   5
Affiliations
Review

Advances in the Diagnosis and Management of Limbal Stem Cell Deficiency

Thanachaporn Kittipibul et al. Cornea. .

Abstract

This concise review focuses on the latest advancements in the diagnosis and management of limbal stem cell deficiency (LSCD). Ensuring the standard of care for individuals affected by LSCD involves the crucial task for physicians to meticulously and accurately diagnose the condition and determine its specific stage. A standardized diagnostic approach forms the foundation for formulating and delivering customized therapeutic interventions to maximize treatment outcomes for each patient. In this review, we introduce a systematic diagnostic algorithm to guide the assessment of LSCD. In addition, the current management algorithm and emerging therapies for LSCD are summarized.

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Conflict of interest statement

The authors have no funding or conflicts of interest to disclose.

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