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. 1985 Feb;21(2):249-50.
doi: 10.1128/jcm.21.2.249-250.1985.

Radioenzymatic assay for trimethoprim in very small serum samples

R Yogev, C Melick, L Tan-Pong

Radioenzymatic assay for trimethoprim in very small serum samples

R Yogev et al. J Clin Microbiol. 1985 Feb.

Abstract

A modification of the methotrexate radioassay kit (supplied by New England Enzyme Center) enabled determination of trimethoprim levels in 5-microliter serum samples. An excellent correlation between this assay and high-pressure liquid chromatography assay was found. These preliminary results suggest that with this method rapid determination of trimethoprim levels in very small samples (5 to 10 microliters) can be achieved.

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References

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    1. Antimicrob Agents Chemother. 1979 Nov;16(5):579-83 - PubMed

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