Reply

Benjamin M Ellingson¹, Francesco Sanvito², Whitney B Pope², Timothy F Cloughesy³, Raymond Y Huang⁴, Javier E Villanueva-Meyer⁵, Daniel P Barboriak⁶, Lalitha K Shankar⁷, Marion Smits⁸, Timothy J Kaufmann⁹, Jerrold L Boxerman¹⁰, Michael Weller¹¹, Evanthia Galanis¹², John de Groot¹³, Susan M Chang¹³, Mark R Gilbert¹⁴, Andrew B Lassman¹⁵, Mark S Shiroishi¹⁶, Ali Nabavizadeh¹⁷, Minesh Mehta¹⁸, Roger Stupp¹⁹, Wolfgang Wick²⁰, David A Reardon²¹, Patrick Y Wen²¹, Michael A Vogelbaum²², Martin van den Bent²³

Affiliations

¹ UCLA Brain Tumor Imaging LaboratoryDepartment of Radiological SciencesDavid Geffen School of MedicineUniversity of California Los AngelesLos Angeles, California bellingson@mednet.ucla.edu.
² UCLA Brain Tumor Imaging LaboratoryDepartment of Radiological SciencesDavid Geffen School of MedicineUniversity of California Los AngelesLos Angeles, California.
³ UCLA Brain Tumor Program, Department of NeurologyDavid Geffen School of MedicineUniversity of California Los AngelesLos Angeles, California.
⁴ Department of RadiologyBrigham and Women's HospitalHarvard Medical SchoolBoston, Massachusetts.
⁵ Departments of Radiology and NeurosurgeryUniversity of CaliforniaSan Francisco, California.
⁶ Department of RadiologyDuke University Medical CenterDurham, North Carolina.
⁷ Clinical Trials Branch, Cancer Imaging ProgramNational Cancer InstituteNational Institutes of HealthBethesda, Maryland.
⁸ Department of Radiology & Nuclear MedicineErasmus MC - University Medical Centre RotterdamRotterdam, The Netherlands.
⁹ Department of RadiologyMayo ClinicRochester, Minnesota.
¹⁰ Department of Diagnostic ImagingRhode Island Hospital and Alpert Medical School of Brown UniversityProvidence, Rhode Island.
¹¹ Department of NeurologyUniversity Hospital and University of ZurichZurich, Switzerland.
¹² Department of OncologyMayo ClinicRochester, Minnesota.
¹³ Division of Neuro-OncologyDepartment of NeurosurgeryUniversity of CaliforniaSan Francisco, California.
¹⁴ Neuro-Oncology BranchCenter for Cancer ResearchNational Cancer InstituteNational Institutes of HealthBethesda, Maryland.
¹⁵ Division of Neuro-OncologyDepartment of NeurologyHerbert Irving Comprehensive Cancer Center and Irving Institute for Clinical and Translational ResearchColumbia University Vagelos College of Physicians and Surgeons and New York-Presbyterian HospitalNew York, New York.
¹⁶ Department of RadiologyKeck School of Medicine of the University of Southern California (USC)Los Angeles, California.
¹⁷ Department of RadiologyPerelman School of MedicineUniversity of PennsylvaniaPhiladelphia, Pennsylvania.
¹⁸ Miami Cancer InstituteMiami, Florida.
¹⁹ Malnati Brain Tumor InstituteLurie Comprehensive Cancer Center and Departments of Neurological SurgeryNeurology and Division of Hematology/OncologyNorthwestern UniversityChicago, Illinois.
²⁰ Department of Neurology Heidelberg University Hospital & Clinical Cooperation Unit NeurooncologyGerman Cancer Consortium (DKTK)German Cancer Research Center (DKFZ)Heidelberg, Germany.
²¹ Center For Neuro-OncologyDana-Farber Cancer Institute and Harvard Medical SchoolBoston, Massachusetts.
²² Department of Neuro-OncologyMoffitt Cancer CenterTampa, Florida.
²³ Department Neuro-OncologyErasmus MC Cancer InstituteRotterdam, The Netherlands.

PMID: 39730160
PMCID: PMC11735428 (available on 2026-01-01)
DOI: 10.3174/ajnr.A8621

Reply

Benjamin M Ellingson et al. AJNR Am J Neuroradiol. 2025.

. 2025 Jan 8;46(1):221-222.

doi: 10.3174/ajnr.A8621.

Authors

Affiliations

¹ UCLA Brain Tumor Imaging LaboratoryDepartment of Radiological SciencesDavid Geffen School of MedicineUniversity of California Los AngelesLos Angeles, California bellingson@mednet.ucla.edu.
² UCLA Brain Tumor Imaging LaboratoryDepartment of Radiological SciencesDavid Geffen School of MedicineUniversity of California Los AngelesLos Angeles, California.
³ UCLA Brain Tumor Program, Department of NeurologyDavid Geffen School of MedicineUniversity of California Los AngelesLos Angeles, California.
⁴ Department of RadiologyBrigham and Women's HospitalHarvard Medical SchoolBoston, Massachusetts.
⁵ Departments of Radiology and NeurosurgeryUniversity of CaliforniaSan Francisco, California.
⁶ Department of RadiologyDuke University Medical CenterDurham, North Carolina.
⁷ Clinical Trials Branch, Cancer Imaging ProgramNational Cancer InstituteNational Institutes of HealthBethesda, Maryland.
⁸ Department of Radiology & Nuclear MedicineErasmus MC - University Medical Centre RotterdamRotterdam, The Netherlands.
⁹ Department of RadiologyMayo ClinicRochester, Minnesota.
¹⁰ Department of Diagnostic ImagingRhode Island Hospital and Alpert Medical School of Brown UniversityProvidence, Rhode Island.
¹¹ Department of NeurologyUniversity Hospital and University of ZurichZurich, Switzerland.
¹² Department of OncologyMayo ClinicRochester, Minnesota.
¹³ Division of Neuro-OncologyDepartment of NeurosurgeryUniversity of CaliforniaSan Francisco, California.
¹⁴ Neuro-Oncology BranchCenter for Cancer ResearchNational Cancer InstituteNational Institutes of HealthBethesda, Maryland.
¹⁵ Division of Neuro-OncologyDepartment of NeurologyHerbert Irving Comprehensive Cancer Center and Irving Institute for Clinical and Translational ResearchColumbia University Vagelos College of Physicians and Surgeons and New York-Presbyterian HospitalNew York, New York.
¹⁶ Department of RadiologyKeck School of Medicine of the University of Southern California (USC)Los Angeles, California.
¹⁷ Department of RadiologyPerelman School of MedicineUniversity of PennsylvaniaPhiladelphia, Pennsylvania.
¹⁸ Miami Cancer InstituteMiami, Florida.
¹⁹ Malnati Brain Tumor InstituteLurie Comprehensive Cancer Center and Departments of Neurological SurgeryNeurology and Division of Hematology/OncologyNorthwestern UniversityChicago, Illinois.
²⁰ Department of Neurology Heidelberg University Hospital & Clinical Cooperation Unit NeurooncologyGerman Cancer Consortium (DKTK)German Cancer Research Center (DKFZ)Heidelberg, Germany.
²¹ Center For Neuro-OncologyDana-Farber Cancer Institute and Harvard Medical SchoolBoston, Massachusetts.
²² Department of Neuro-OncologyMoffitt Cancer CenterTampa, Florida.
²³ Department Neuro-OncologyErasmus MC Cancer InstituteRotterdam, The Netherlands.

PMID: 39730160
PMCID: PMC11735428 (available on 2026-01-01)
DOI: 10.3174/ajnr.A8621

No abstract available

PubMed Disclaimer

Cited by

RANO 2.0: critical updates and practical considerations for radiological assessment in neuro-oncology.
Sakata A, Fushimi Y, Oshima S, Uto M, Mineharu Y, Nakajima S, Okuchi S, Yamamoto T, Otani S, Ikeda S, Takada S, Mizowaki T, Arakawa Y, Nakamoto Y. Sakata A, et al. Jpn J Radiol. 2025 Jun 30. doi: 10.1007/s11604-025-01821-6. Online ahead of print. Jpn J Radiol. 2025. PMID: 40586994 Review.

References

1. Ellingson BM, Sanvito F, Cloughesy TF, et al. . A neuroradiologist’s guide to operationalizing the Response Assessment in Neuro-Oncology (RANO) Criteria Version 2.0 for gliomas in adults. AJNR Am J Neuroradiol 2024;45:1846–56 10.3174/ajnr.A8396 - DOI - PMC - PubMed
1. Wen PY, Van Den Bent MJ, Youssef G, et al. . RANO 2.0: Update to the Response Assessment in Neuro-Oncology criteria for high- and low-grade gliomas in adults. J Clin Oncol 2023;41:5187–99 10.1200/JCO.23.01059 - DOI - PMC - PubMed
1. Sanvito F, Castellano A, Cloughesy TF, et al. . RANO 2.0 criteria: concepts applicable to the neuroradiologist’s clinical practice. Curr Opin Oncol 10.1097/CCO.0000000000001077 - DOI - PMC - PubMed
1. Youssef G, Rahman R, Bay C, et al. . Evaluation of Standard Response Assessment in Neuro-Oncology, Modified Response Assessment in Neuro-Oncology, and Immunotherapy Response Assessment in Neuro-Oncology in Newly Diagnosed and Recurrent Glioblastoma. J Clin Oncol Off J Am Soc Clin Oncol 2023;41:3160–71 10.1200/JCO.22.01579 - DOI - PubMed
1. Weinberg BD, Gore A, Shu H-KG, et al. . Management-based structured reporting of posttreatment glioma response with the Brain Tumor Reporting and Data System. J Am Coll Radiol 2018;15:767–71 10.1016/j.jacr.2018.01.022 - DOI - PubMed

Grants and funding

LinkOut - more resources

Full Text Sources
- HighWire

Save citation to file

Email citation

Add to Collections

Add to My Bibliography

Your saved search

Create a file for external citation management software

Your RSS Feed

Reply

Affiliations

Reply

Authors

Affiliations

Similar articles

Cited by

References

Grants and funding

LinkOut - more resources

Full Text Sources