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Review
. 2025 Mar:292:139171.
doi: 10.1016/j.ijbiomac.2024.139171. Epub 2024 Dec 26.

Exploring the therapeutic potential of biosynthetic enzymes in cancer treatment: Innovations and implications

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Review

Exploring the therapeutic potential of biosynthetic enzymes in cancer treatment: Innovations and implications

Afeeza Klg et al. Int J Biol Macromol. 2025 Mar.

Abstract

Cancer remains a major global health concern due to several factors. These include the difficulty in accessing effective drugs, the high toxicity of available treatments, and the emergence of resistance to therapy. As a result, alternative strategies, such as the use of microbial enzymes, have gained attention as potential solutions to these challenges. Microbial enzymes have shown promise in inhibiting the uncontrolled growth of tumor cells through various mechanisms. In this comprehensive review, our objective is to emphasize the importance of pivotal microbial enzymes in fighting cancer and their ability to hinder the growth of tumors or cancer cells. The review article serves as a scientific roadmap for researchers, clinicians, and industry stakeholders exploring the therapeutic potential of biosynthetic enzymes in cancer treatment. It emphasizes the quest for effective and sustainable cancer therapies, presenting the possibility of personalized treatments with fewer side effects than traditional therapies.

Keywords: Biosynthetic enzymes; Enzyme therapy; Therapeutic potential; cancer therapy.

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Conflict of interest statement

Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

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