Clinical promise and applications of epigenetic biomarkers

G Bea A Wisman¹, Tomasz K Wojdacz², Lucia Altucci^{3

4

5

6}, Marianne G Rots⁷, Dawn L DeMeo⁸, Harold Snieder⁹

Affiliations

¹ Department of Gynecologic Oncology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands. g.b.a.wisman@umcg.nl.
² Independent Clinical Epigenetics Laboratory, Pomeranian Medical University, Szczecin, Poland.
³ Dipartimento di Medicina di Precisione, Università degli Studi della Campania "Luigi Vanvitelli" Napoli, Napoli, Italy.
⁴ Biogem, Molecular Biology and Genetics Research Institute, Ariano Irpino, Italy.
⁵ IEOS CNR, Naples, Italy.
⁶ Medical Epigenetics Program, Azienda Ospedaliera Universitaria "Luigi Vanvitelli", Naples, Italy.
⁷ Department of Pathology and Medical Biology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
⁸ Channing Division of Network Medicine and Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, USA.
⁹ Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands. h.snieder@umcg.nl.

Editorial

G Bea A Wisman et al. Clin Epigenetics. 2024.

. 2024 Dec 28;16(1):192.

doi: 10.1186/s13148-024-01806-8.

G Bea A Wisman¹, Tomasz K Wojdacz², Lucia Altucci^{3

4

5

6}, Marianne G Rots⁷, Dawn L DeMeo⁸, Harold Snieder⁹

¹ Department of Gynecologic Oncology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands. g.b.a.wisman@umcg.nl.
² Independent Clinical Epigenetics Laboratory, Pomeranian Medical University, Szczecin, Poland.
³ Dipartimento di Medicina di Precisione, Università degli Studi della Campania "Luigi Vanvitelli" Napoli, Napoli, Italy.
⁴ Biogem, Molecular Biology and Genetics Research Institute, Ariano Irpino, Italy.
⁵ IEOS CNR, Naples, Italy.
⁶ Medical Epigenetics Program, Azienda Ospedaliera Universitaria "Luigi Vanvitelli", Naples, Italy.
⁷ Department of Pathology and Medical Biology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
⁸ Channing Division of Network Medicine and Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, USA.
⁹ Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands. h.snieder@umcg.nl.

No abstract available

Figures

1. Berdasco M, Esteller M. Clinical epigenetics: seizing opportunities for translation. Nat Rev Genet. 2019;20(2):109–27. - PubMed
1. Hanahan D. Hallmarks of cancer: new dimensions. Cancer Discov. 2022;12(1):31–46. - PubMed
1. Butler M, Pongor L, Su YT, Xi L, Raffeld M, Quezado M, et al. MGMT status as a clinical biomarker in glioblastoma. Trends Cancer. 2020;6(5):380–91. - PMC - PubMed
1. de Waard J, Bhattacharya A, de Boer MT, van Hemel BM, Esajas MD, Vermeulen KM, et al. Identification of a methylation panel as an alternative triage to detect CIN3+ in hrHPV-positive self-samples from the population-based cervical cancer screening programme. Clin Epigenetics. 2023;15(1):103. - PMC - PubMed
1. Lu H, Liu Y, Wang J, Fu S, Wang L, Huang C, et al. Detection of ovarian cancer using plasma cell-free DNA methylomes. Clin Epigenetics. 2022;14(1):74. - PMC - PubMed