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Editorial
. 2024 Dec 16:15:1533289.
doi: 10.3389/fimmu.2024.1533289. eCollection 2024.

Editorial: Tumor-draining lymph nodes

Maximilian Seidl  1 , Nikolas Hendrik Stoecklein  2 , Dennis Jones  3
Affiliations
Editorial

Editorial: Tumor-draining lymph nodes

Maximilian Seidl et al. Front Immunol. .
No abstract available

Keywords: immune suppression; immunotherapy; metastasis; prognosis; tumor draining lymph node; tumor immunology.

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Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Figures

Figure 1
Figure 1
Summary of Research Topic (adapted from Lei et al.). The comprehensive review by Lei et al. summarizes cancer cell metastasis to lymph nodes and the metabolic changes cancer cells undergo to establish lymph node metastasis and further metastasize. In addition, the review highlights the stromal and cellular consequences of lymph node metastasis that define lymph node function. The study by Kooreman et al. evaluates lymph node (metastasis-free) shape and the association with nodal function and patient prognosis. Bravo et al. identify a triad of factors in the paracortex of metastatic lymph nodes—high endothelial venules, dendritic cells, and lymphocytes—that were predictive of patient response to subsequent vaccination and overall survival. Piersiala et al. identified the expression of multiple immune inhibitory receptors on T cells within tumor-draining lymph nodes as being associated with worse disease-free survival.
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  • Editorial on the Research Topic Tumor-draining lymph nodes

References

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