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. 2024 Dec 31;21(1):340.
doi: 10.1186/s12985-024-02594-6.

Molecular epidemiological analysis of Influenza viruses in Influenza-like illness cases: a retrospective study in Chongqing Hi-Tech Zone, China (2021-2024)

Wei Cai #  1 , Yuhang Deng  1 , Pan Xu  1 , Jianjiang Xue  2
Affiliations

Molecular epidemiological analysis of Influenza viruses in Influenza-like illness cases: a retrospective study in Chongqing Hi-Tech Zone, China (2021-2024)

Wei Cai et al. Virol J. .

Abstract

Objectives: To analyze the molecular epidemiological characteristics of influenza viruses in influenza-like cases in Chongqing Hi-Tech Zone, China, to provide data support and a scientific basis for optimizing influenza prevention and control strategies in the region.

Materials and methods: A retrospective analysis was conducted on the molecular epidemiological characteristics of influenza viruses in influenza-like cases at a hospital in Chongqing Hi-Tech Zone from 2021 to 2024. Colloidal gold detection of viral antibodies, fluorescent PCR detection of nucleic acids, and gene sequencing were used to identify the different subtypes.

Results: Among 39,986 ILI specimens tested using the immunocolloid gold method, 6,616 influenza viruses were detected, with a detection rate of 16.54%. Infections included 4,464 influenza A viruses (67.50%), 2,033 influenza B viruses (30.73%), and 119 co-infections of influenza A and B viruses (1.77%).In this region, H3N2 was the predominant subtype of influenza A, and Victoria was the main subtype of influenza B.

Conclusion: Influenza epidemics in the winter and spring seasons in Chongqing Hi-Tech Zone were predominantly caused by influenza A, with influenza B also circulating. Influenza A strains were mainly H3N2, while influenza B strains were primarily Victoria.

Keywords: Influenza viruses; Influenza-like illness cases; Molecular epidemiological analysis; Prevention and control.

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Conflict of interest statement

Declarations. Competing interests: The authors declare no competing interests.

Figures

Fig. 1
Fig. 1
Temporal distribution of influenza virus epidemics
Fig. 2
Fig. 2
Percentage of influenza virus test results for ILI specimens
Fig. 3
Fig. 3
Ratio of SAA and CRP levels in patients with Stream A and Stream B from April 2023 to April 2024Comparison of data from [M(P25, P75), mg/L]
See this image and copyright information in PMC

References

    1. HU R, Yan-Liang Zhang, Juan Zhang. Research progress of influenza A and B virus detection methods. Systemic Med 2023,8(2):178–182198.
    1. Wang Jiang Xu, Yi Chen, Junfeng, et al. Progress in laboratory detection of influenza virus. Chin J Hosp Infect. 2020;30(02):308–12.
    1. Petrova VN, Russell CA. The evolution of seasonal influenzaviruses. Nat Rev Microbiol. 2018;16(1):47–60. - DOI - PubMed
    1. Zhi-Ou FU, Chang-Jun B, Zhong-Jie LI, Li-Ping WANG, Yuan LI, Han-Bing L, Zhi-Xing PENG. Progress of influenza early warning research based on big data. Chin J Epidemiol 2020,41(6):975–80. - PubMed
    1. Yu Juan, Li H, Rao HX, et al. Analysis of respiratory virus detection in nasopharyngeal secretions of 150 influenza-like cases negative for influenza virus nucleic acid during the high influenza season. Shandong Med. 2018;58(31):40–3.

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