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Review
. 2024 Dec 24;25(12):455.
doi: 10.31083/j.rcm2512455. eCollection 2024 Dec.

Hemodynamics in Left-Sided Cardiomyopathies

Guido Del Monaco  1   2 , Francesco Amata  1   2 , Vincenzo Battaglia  1   2 , Cristina Panico  1   2 , Gianluigi Condorelli  1   2 , Giuseppe Pinto  1
Affiliations
Review

Hemodynamics in Left-Sided Cardiomyopathies

Guido Del Monaco et al. Rev Cardiovasc Med. .

Abstract

Cardiomyopathies, historically regarded as rare, are increasingly recognized due to advances in imaging diagnostics and heightened clinical focus. These conditions, characterized by structural and functional abnormalities of the myocardium, pose significant challenges in both chronic and acute patient management. A thorough understanding of the hemodynamic properties, specifically the pressure-volume relationships, is essential. These relationships provide insights into cardiac function, including ventricular compliance, contractility, and overall cardiovascular performance. Despite their potential utility, pressure-volume curves are underutilized in clinical settings due to the invasive nature of traditional measurement techniques. Recognizing the dynamic nature of cardiomyopathies, with possible transitions between phenotypes, underscores the importance of continuous monitoring and adaptive therapeutic strategies. Enhanced hemodynamic evaluation can facilitate tailored treatment, potentially improving outcomes for patients with these complex cardiac conditions.

Keywords: cardiac catheterization; cardiomyopathies; hemodynamics; pressure-volume relationship.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Fig. 1.
Fig. 1.
Pressure-volume loops in HCM compared to normal hearts. Abbreviations: EDPVR, end-diastolic pressure-volume relationship; ESPVR, end-systolic pressure-volume relationship; ESV, end-systolic volume; HCM, hypertrophic cardiomyopathy; LV, left ventricle; LVEDP, left ventricular end-diastolic pressure; LVOT, left ventricular outflow tract; MV, mid ventricular; SV, stroke volume. ↑ increase, ↓ decrease, = no change.
Fig. 2.
Fig. 2.
Pressure-volume loops in DCM in initial phases compared to normal heart. Abbreviations: DCM, dilated cardiomyopathy; EDPVR, end-diastolic pressure-volume relationship; EDV, end-diastolic volume; ESPVR, end-systolic pressure-volume relationship; ESV, end-systolic volume; LV, left ventricle; SV, stroke volume. ↑ increase, ↓ decrease.
Fig. 3.
Fig. 3.
Pressure-Volume loops in RCM compared to normal hearts. Abbreviations: EDPVR, end-diastolic pressure-volume relationship; EDV, end-diastolic volume; ESPVR, end-systolic pressure-volume relationship; ESV, end-systolic volume; LV, left ventricle; RCM, restrictive cardiomyopathy; SV, stroke volume. ↑ increase, ↓ decrease, = no change.
See this image and copyright information in PMC

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