Impact of Environmental Exposures on the Development and Progression of Fibrotic Interstitial Lung Disease

Kerri A Johannson^{1

2}, Ayodeji Adegunsoye³, Jürgen Behr⁴, Vincent Cottin^{5

6}, Allan R Glanville⁷, Marilyn K Glassberg⁸, Gillian C Goobie^{9

10

11}, R Gisli Jenkins^{12

13}, John S Kim¹⁴, Cathryn T Lee³, Carrie A Redlich¹⁵, Luca Richeldi¹⁶, Margaret L Salisbury¹⁷, Terry Tetley¹⁸, Tamera J Corte¹⁹

Affiliations

¹ Department of Medicine and.
² Snyder Institute for Chronic Diseases, University of Calgary, Calgary, Alberta, Canada.
³ Department of Medicine, University of Chicago, Chicago, Illinois.
⁴ Department of Medicine V, Ludwig Maximilian University Hospital, German Center for Lung Research, Ludwig Maximilian University Munich, Munich, Germany.
⁵ Department of Respiratory Medicine, National Reference Centre for Rare Pulmonary Diseases, European Respiratory Network- Respiratory Diseases, Louis Pradel Hospital, Lyon Public Hospitals, Lyon, France.
⁶ Mixed Research Unit 754, French National Research Institute for Agriculture, Food and Environment, Claude Bernard University Lyon 1, Lyon, France.
⁷ Macquarie Respiratory and Sleep Unit, Macquarie University, Sydney, New South Wales, Australia.
⁸ Department of Medicine, Loyola University Chicago Stritch School of Medicine, Maywood, Illinois.
⁹ Centre for Heart Lung Innovation, St. Paul's Hospital, University of British Columbia, Vancouver, British Columbia, Canada.
¹⁰ Division of Respiratory Medicine, Department of Medicine, University of British Columbia, Vancouver, British Columbia, Canada.
¹¹ Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania.
¹² National Heart and Lung Institute, National Institute for Health and Care Research Imperial Biomedical Research Centre, Imperial College London, London, United Kingdom.
¹³ Interstitial Lung Disease Centre, Royal Brompton and Harefield Hospital, London, United Kingdom.
¹⁴ Department of Medicine, University of Virginia School of Medicine, Charlottesville, Virginia.
¹⁵ Department of Medicine, Yale School of Medicine, New Haven, Connecticut.
¹⁶ Fondazione Policlinico Universitario Agostino Gemelli, Istituto di Ricovero e Cura a Carattere Scientifico, Università Cattolica del Sacro Cuore, Rome, Italy.
¹⁷ Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee.
¹⁸ Lung Cell Biology, Airways Disease, National Heart and Lung Institute, Imperial College London, London, United Kingdom; and.
¹⁹ Department of Respiratory Medicine, Royal Prince Alfred Hospital and University of Sydney, Sydney, New South Wales, Australia.

PMID: 39745380
DOI: 10.1164/rccm.202409-1730PP

Impact of Environmental Exposures on the Development and Progression of Fibrotic Interstitial Lung Disease

Kerri A Johannson et al. Am J Respir Crit Care Med. 2025 Apr.

. 2025 Apr;211(4):560-568.

doi: 10.1164/rccm.202409-1730PP.

Authors

Affiliations

¹ Department of Medicine and.
² Snyder Institute for Chronic Diseases, University of Calgary, Calgary, Alberta, Canada.
³ Department of Medicine, University of Chicago, Chicago, Illinois.
⁴ Department of Medicine V, Ludwig Maximilian University Hospital, German Center for Lung Research, Ludwig Maximilian University Munich, Munich, Germany.
⁵ Department of Respiratory Medicine, National Reference Centre for Rare Pulmonary Diseases, European Respiratory Network- Respiratory Diseases, Louis Pradel Hospital, Lyon Public Hospitals, Lyon, France.
⁶ Mixed Research Unit 754, French National Research Institute for Agriculture, Food and Environment, Claude Bernard University Lyon 1, Lyon, France.
⁷ Macquarie Respiratory and Sleep Unit, Macquarie University, Sydney, New South Wales, Australia.
⁸ Department of Medicine, Loyola University Chicago Stritch School of Medicine, Maywood, Illinois.
⁹ Centre for Heart Lung Innovation, St. Paul's Hospital, University of British Columbia, Vancouver, British Columbia, Canada.
¹⁰ Division of Respiratory Medicine, Department of Medicine, University of British Columbia, Vancouver, British Columbia, Canada.
¹¹ Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania.
¹² National Heart and Lung Institute, National Institute for Health and Care Research Imperial Biomedical Research Centre, Imperial College London, London, United Kingdom.
¹³ Interstitial Lung Disease Centre, Royal Brompton and Harefield Hospital, London, United Kingdom.
¹⁴ Department of Medicine, University of Virginia School of Medicine, Charlottesville, Virginia.
¹⁵ Department of Medicine, Yale School of Medicine, New Haven, Connecticut.
¹⁶ Fondazione Policlinico Universitario Agostino Gemelli, Istituto di Ricovero e Cura a Carattere Scientifico, Università Cattolica del Sacro Cuore, Rome, Italy.
¹⁷ Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee.
¹⁸ Lung Cell Biology, Airways Disease, National Heart and Lung Institute, Imperial College London, London, United Kingdom; and.
¹⁹ Department of Respiratory Medicine, Royal Prince Alfred Hospital and University of Sydney, Sydney, New South Wales, Australia.