Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2025 Jan 2;25(1):3.
doi: 10.1186/s12888-024-06445-0.

The Bergen 4-Day Treatment for panic disorder patients in a rural clinical setting: a long-term follow-up study

Thorstein Olsen Eide  1   2   3 , Thorbjørn Olsen  4 , Hans Hansen  5 , Bjarne Hansen  2   3 , Stian Solem  6 , Kristen Hagen  7   8   9
Affiliations

The Bergen 4-Day Treatment for panic disorder patients in a rural clinical setting: a long-term follow-up study

Thorstein Olsen Eide et al. BMC Psychiatry. .

Abstract

Background: The Bergen 4-Day Treatment (B4DT) is a concentrated cognitive behaviour therapy (CBT) approach that has shown promise in treating panic disorder (PD). However, the effectiveness of the B4DT, particularly regarding long-term outcomes in rural clinical settings, remains underexplored.

Methods: A total of 58 patients were included using a naturalistic open-label trial design. Patients were assessed at 12-month follow-up. Measures included the Panic Disorder Severity Scale (PDSS), the Patient Health Questionnaire-9 (PHQ-9), and the Generalized Anxiety Disorder-7 scale (GAD-7).

Results: The study revealed significant and lasting reductions in PD symptoms, with a high rate of remission maintained at 12-month follow-up (82.8%). Regarding the secondary outcomes, significant improvements in symptoms of depression and generalized anxiety were also shown.

Conclusions: The B4DT represents a promising treatment approach for PD, demonstrating stable long-term outcomes in rural settings. This finding supports the potential of concentrated CBT formats in achieving sustained symptom improvement in patients with PD, warranting further investigation and broader implementation.

Trial registration: The study was reviewed by the Regional Committee for Medical Research Ethics Northern Norway, REK North (REK Nord2021/273145).

Keywords: Bergen 4-Day treatment; Cognitive behavioural therapy; Long-term effectiveness; Panic disorder; Rural clinical setting.

PubMed Disclaimer

Conflict of interest statement

Declarations. Ethics approval and consent to participate: The study was conducted in accordance with the principles outlined in the Declaration of Helsinki and was reviewed by the Regional Committee for Medical Research Ethics Northern Norway, REK North (REK Nord-2021/273145). Informed written consent was obtained from all participants. The participants were informed that participation in the study was voluntary and that they had the right to withdraw from the study at any time without any negative effect on their treatment. All methods were performed in accordance with the relevant guidelines and regulations. Consent for publication: Not applicable. Competing interests: The authors declare no competing interests.

References

    1. American Psychiatric Association. Diagnostic and statistical manual of mental disorders. 5th ed. Washington, DC2013.
    1. Davidoff J, Christensen S, Khalili DN, Nguyen J, IsHak WW. Quality of life in panic disorder: looking beyond symptom remission. Qual Life Res. 2012;21(6):945–59. - PubMed
    1. Bonham CA, Uhlenhuth E. Disability and comorbidity: diagnoses and symptoms associated with disability in a clinical population with panic disorder. Psychiatry J. 2014;2014:619727. - PMC - PubMed
    1. de Jonge P, Roest AM, Lim CC, Florescu SE, Bromet EJ, Stein DJ, et al. Cross-national epidemiology of panic disorder and panic attacks in the world mental health surveys. Depress Anxiety. 2016;33(12):1155–77. - PMC - PubMed
    1. Cuijpers P, Gentili C, Banos RM, Garcia-Campayo J, Botella C, Cristea IA. Relative effects of cognitive and behavioral therapies on generalized anxiety disorder, social anxiety disorder and panic disorder: a meta-analysis. J Anxiety Disord. 2016;43:79–89. - PubMed

Publication types

LinkOut - more resources