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. 2025 Jan 2;13(1):e70037.
doi: 10.1002/ccr3.70037. eCollection 2025 Jan.

Primary Leiomyosarcoma of the Kidney: A Case Report

Srijana Khati  1 , Sagar Rana Magar  2 , Ankita Simkhada  1 , Ramesh Paudel  1 , Surendra Khanal  2 , Bishal Panthi  1 , Sadmarg Thakur  2 , Sujan Paudel  2 , Prajjwol Luitel  2
Affiliations

Primary Leiomyosarcoma of the Kidney: A Case Report

Srijana Khati et al. Clin Case Rep. .

Abstract

Primary renal leiomyosarcoma is a rare but highly aggressive tumor with a poor prognosis. Early detection and surgical excision provide the most effective initial treatment. However, vigilant postoperative surveillance is critical due to the elevated risk of tumor recurrence and metastasis, as seen in this case.

Keywords: case report; leiomyosarcoma; malignancy; renal; sarcoma.

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Conflict of interest statement

The authors declare no conflicts of interest.

Figures

FIGURE 1
FIGURE 1
Gross specimen of the right kidney: Cut section of the kidney showing a heterogenous tumor showing gray‐white homogenous area with whorling pattern (black arrow) and areas of necrosis and hemorrhage (red arrow).
FIGURE 2
FIGURE 2
Hematoxylin and eosin (H&E) stain, (×100). Left: Tumor composed of spindle cells arranged in interlacing bundles and fascicles. Right: Tumor cells with oval to elongated nuclei having blunted ends.
FIGURE 3
FIGURE 3
Immunohistochemical staining. Left: Tumor cells with cytoplasmic immunopositivity for SMA (×400). Right: Tumor cells with focal, weak immunopositivity for desmin. (×400).
See this image and copyright information in PMC

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References

    1. Ozturk H., “High‐Grade Primary Renal Leiomyosarcoma,” International Brazilian Journal of Urology 41, no. 2 (2015): 304–311, 10.1590/S1677-5538.IBJU.2015.02.17. - DOI - PMC - PubMed
    1. Dhawan S., Chopra P., and Dhawan S., “Primary Renal Leiomyosarcoma: A Diagnostic Challenge,” Urology Annals 4, no. 1 (2012): 48–50, 10.4103/0974-7796.91623. - DOI - PMC - PubMed
    1. Novak M., Perhavec A., Maturen K. E., Pavlovic Djokic S., Jereb S., and Erzen D., “Leiomyosarcoma of the Renal Vein: Analysis of Outcome and Prognostic Factors in the World Case Series of 67 Patients,” Radiol Oncologia 51 (2016): 56–64, 10.1515/RAON-2016-0051. - DOI - PMC - PubMed
    1. Sohrabi C., Mathew G., Maria N., Kerwan A., Franchi T., and Agha R. A., “The SCARE 2023 Guideline: Updating Consensus Surgical CAse REport (SCARE) Guidelines,” International Journal of Surgery 109, no. 5 (2023): 1136–1140, 10.1097/JS9.0000000000000373. - DOI - PMC - PubMed
    1. George S., Serrano C., Hensley M. L., and Ray‐Coquard I., “Soft Tissue and Uterine Leiomyosarcoma,” Journal of Clinical Oncology 36, no. 2 (2018): 144–150, 10.1200/JCO.2017.75.9845. - DOI - PMC - PubMed

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