Catastrophic antiphospholipid antibody syndrome associated with ischaemic cardiomyopathy

Abstract

We report the case of a 16-year-old female with previously diagnosed bilateral sub-segmental pulmonary emboli who presented in cardiogenic shock from depressed biventricular function with cardiac MRI demonstrating concern for microvascular coronary injury. She was ultimately diagnosed with catastrophic antiphospholipid antibody syndrome-induced ischaemic cardiomyopathy, potentially associated with an underlying autoimmune connective tissue disease.

Keywords: cardiomyopathy; catastrophic antiphospholipid antibody syndrome; heart failure.