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. 2025 Aug;54(8):1621-1630.
doi: 10.1007/s00256-024-04861-7. Epub 2025 Jan 6.

MRI grading using the neuropathy score-reporting and data system with electrodiagnostic correlation in radial neuropathy around the elbow: a 13-year retrospective review

Benjamin Abiri  1 , David Kopylov  1 , Mohammad Samim  1 , William Walter  1 , Jan Fritz  1 , Iman Khodarahmi  1 , Christopher J Burke  2
Affiliations

MRI grading using the neuropathy score-reporting and data system with electrodiagnostic correlation in radial neuropathy around the elbow: a 13-year retrospective review

Benjamin Abiri et al. Skeletal Radiol. 2025 Aug.

Abstract

Objective: To evaluate the Neuropathy Score-Reporting and Data System (NS-RADS) MRI grading system in conjunction with electrodiagnostic (EDx) testing for radial neuropathy at the elbow.

Materials and methods: Patients presenting between 2010 and 2023 with suspected radial neuropathy who underwent both EDx testing in the form of electromyography and nerve conduction studies and MRI within a 12-month period were evaluated. Three blinded radiologists used the NS-RADS grading system to evaluate nerve entrapment (E grades), muscle denervation (M grades) proximally within the supinator/extensor carpi radialis brevis (ECRB), and more distally within the forearm extensor muscles. These grades and the presence of lateral epicondylitis were then correlated with EDx abnormalities.

Results: Forty-nine participants were included. Inter-reader reliability for M grades in the forearm extensor muscles was good (ICC = 0.90 [95% CI = 0.83 - 0.94], p < 0.001), as was reliability for the supinator/ECRB muscles (ICC = 0.91 [95% CI = 0.86-0.95], p < 0.001). Inter-reader reliability for E grades was moderate (ICC = 0.83 [95% CI = 0.69-0.90], p < 0.001). Patients with positive EDx studies had a significantly different distribution of M grades for the forearm extensors and supinator/ECRB than those with negative studies (all p values < 0.001). However, overall consensus reads showed no significant difference in the distribution of E grades between patients with positive and negative EDx studies.

Conclusion: Muscle grading strongly correlated with EDx positivity, with a high level of inter-reader agreement for muscle denervation-related alterations. Nerve grading, however, did not show a statistical correlation.

Keywords: Electrodiagnostic; MRI; Neuropathy; Radial.

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Conflict of interest statement

Declarations. Ethical approval: All procedures performed in studies involving human subjects were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards. This study was approved by the IRB. Conflict of interest: The authors declare no competing interests.

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References

    1. Stanley J. Radial tunnel syndrome: a surgeon’s perspective. J Hand Ther. 2006;19(2):180–4. - DOI - PubMed
    1. Dang AC, Rodner CM. Unusual compression neuropathies of the forearm, part I: radial nerve. J Hand Surg Am. 2009;34(10):1906–14. - DOI - PubMed
    1. Węgiel A, Karauda P, Zielinska N, Tubbs RS, Olewnik Ł. Radial nerve compression: anatomical perspective and clinical consequences. Neurosurg Rev. 2023;46(1):53. - DOI - PubMed - PMC
    1. Clavert P, Lutz JC, Adam P, Wolfram-Gabel R, Liverneaux P, Kahn JL. Frohse’s arcade is not the exclusive compression site of the radial nerve in its tunnel. Orthop Traumatol Surg Res. 2009;95(2):114–8. - DOI - PubMed
    1. Chien AJ, Jamadar DA, Jacobson JA, Hayes CW, Louis DS. Sonography and MR imaging of posterior interosseous nerve syndrome with surgical correlation. AJR Am J Roentgenol. 2003;181(1):219–21. - DOI - PubMed

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