CANAIRI: the Collaboration for Translational Artificial Intelligence Trials in healthcare

Melissa D McCradden^{1

2

3}, Alex John London⁴, Judy Wawira Gichoya⁵, Mark Sendak⁶, Lauren Erdman^{7

8}, Ian Stedman⁹, Lauren Oakden-Rayner¹⁰, Ismail Akrout¹¹, James A Anderson^{12

13

14}, Lesley-Anne Farmer¹⁵, Robert Greer¹¹, Anna Goldenberg^{12

16

17

18}, Yvonne Ho^{19

20}, Shalmali Joshi^{21

22}, Jennie Louise^{23

24}, Muhammad Mamdani^{17

25

26}, Mjaye L Mazwi²⁷, Abdullahi Mohamud^{12

11}, Lyle J Palmer^{10

28}, Antonios Peperidis²⁹, Stephen R Pfohl³⁰, Mandy Rickard³¹, Carolyn Semmler^{10

32}, Karandeep Singh³³, Devin Singh^{12

11}, Seyi Soremekun³⁴, Lana Tikhomirov^{10

32}, Anton H van der Vegt³⁵, Karin Verspoor³⁶, Xiaoxuan Liu^{37

38

39}

Affiliations

¹ Women's and Children's Health Network, Adelaide, South Australia, Australia. melissa.mccradden@adelaide.edu.au.
² Australian Institute for Machine Learning, University of Adelaide, Adelaide, South Australia, Australia. melissa.mccradden@adelaide.edu.au.
³ SickKids Research Institute, Toronto, Ontario, Canada. melissa.mccradden@adelaide.edu.au.
⁴ Carnegie Mellon University, Pittsburgh, PA, USA.
⁵ Department of Radiology, Emory University, Atlanta, GA, USA.
⁶ Duke Institute for Health Innovation, Durham, NC, USA.
⁷ James M. Anderson Center for Health Systems Excellence, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
⁸ University of Cincinnati School of Medicine, Cincinnati, OH, USA.
⁹ School of Public Policy and Administration at York University, Toronto, Ontario, Canada.
¹⁰ Australian Institute for Machine Learning, University of Adelaide, Adelaide, South Australia, Australia.
¹¹ Artificial Intelligence in Medicine Initiative, The Hospital for Sick Children, Toronto, Ontario, Canada.
¹² SickKids Research Institute, Toronto, Ontario, Canada.
¹³ Department of Bioethics, The Hospital for Sick Children, Toronto, Ontario, Canada.
¹⁴ Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, Ontario, Canada.
¹⁵ Tethyan Consulting, Canberra, Australian Capital Territory, Australia.
¹⁶ School of Computer Science, University of Toronto, Toronto, Ontario, Canada.
¹⁷ Vector Institute for AI, Toronto, Ontario, Canada.
¹⁸ Canadian Institute for Advanced Research, Toronto, Ontario, Canada.
¹⁹ Royal Australian and New Zealand College of Radiologists, Sydney, New South Wales, Australia.
²⁰ Medical Devices and Product Quality Division, Health Products and Regulation Group, Australian Government Department of Health and Aged Care, Canberra, Australian Capital Territory, Australia.
²¹ Biomedical Informatics, Columbia University, New York, NY, USA.
²² Columbia University Irving Medical Center, New York, NY, USA.
²³ Women's and Children's Hospital Research Centre, Adelaide, South Australia, Australia.
²⁴ Biostatistics Unit, South Australian Health and Medical Research Institute, Adelaide, South Australia, Australia.
²⁵ Unity Health, Toronto, Ontario, Canada.
²⁶ Temerty Centre for Artificial Intelligence Research and Education in Medicine (T-CAIREM), University of Toronto, Toronto, Ontario, Canada.
²⁷ Seattle Children's Hospital, Seattle, WA, USA.
²⁸ School of Public Health, University of Adelaide, Adelaide, South Australia, Australia.
²⁹ Cropify, Adelaide, South Australia, Australia.
³⁰ Google Research, Mountain View, CA, USA.
³¹ Division of Urology, Department of Surgery, The Hospital for Sick Children, Toronto, Ontario, Canada.
³² School of Psychology, University of Adelaide, Adelaide, South Australia, Australia.
³³ Division of Biomedical Informatics, Department of Medicine, University of California San Diego, San Diego, CA, USA.
³⁴ Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, UK.
³⁵ Queensland Digital Health Centre, University of Queensland, Brisbane, Queensland, Australia.
³⁶ School of Computing Technologies, RMIT University, Melbourne, VIC, Australia.
³⁷ Institute of Inflammation and Ageing, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK.
³⁸ University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK.
³⁹ National Institute for Health and Care Research, Birmingham Biomedical Research Centre, University of Birmingham, Birmingham, UK.

PMID: 39762426
DOI: 10.1038/s41591-024-03364-1

CANAIRI: the Collaboration for Translational Artificial Intelligence Trials in healthcare

Melissa D McCradden et al. Nat Med. 2025 Jan.

. 2025 Jan;31(1):9-11.

doi: 10.1038/s41591-024-03364-1.

Authors

Affiliations

¹ Women's and Children's Health Network, Adelaide, South Australia, Australia. melissa.mccradden@adelaide.edu.au.
² Australian Institute for Machine Learning, University of Adelaide, Adelaide, South Australia, Australia. melissa.mccradden@adelaide.edu.au.
³ SickKids Research Institute, Toronto, Ontario, Canada. melissa.mccradden@adelaide.edu.au.
⁴ Carnegie Mellon University, Pittsburgh, PA, USA.
⁵ Department of Radiology, Emory University, Atlanta, GA, USA.
⁶ Duke Institute for Health Innovation, Durham, NC, USA.
⁷ James M. Anderson Center for Health Systems Excellence, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
⁸ University of Cincinnati School of Medicine, Cincinnati, OH, USA.
⁹ School of Public Policy and Administration at York University, Toronto, Ontario, Canada.
¹⁰ Australian Institute for Machine Learning, University of Adelaide, Adelaide, South Australia, Australia.
¹¹ Artificial Intelligence in Medicine Initiative, The Hospital for Sick Children, Toronto, Ontario, Canada.
¹² SickKids Research Institute, Toronto, Ontario, Canada.
¹³ Department of Bioethics, The Hospital for Sick Children, Toronto, Ontario, Canada.
¹⁴ Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, Ontario, Canada.
¹⁵ Tethyan Consulting, Canberra, Australian Capital Territory, Australia.
¹⁶ School of Computer Science, University of Toronto, Toronto, Ontario, Canada.
¹⁷ Vector Institute for AI, Toronto, Ontario, Canada.
¹⁸ Canadian Institute for Advanced Research, Toronto, Ontario, Canada.
¹⁹ Royal Australian and New Zealand College of Radiologists, Sydney, New South Wales, Australia.
²⁰ Medical Devices and Product Quality Division, Health Products and Regulation Group, Australian Government Department of Health and Aged Care, Canberra, Australian Capital Territory, Australia.
²¹ Biomedical Informatics, Columbia University, New York, NY, USA.
²² Columbia University Irving Medical Center, New York, NY, USA.
²³ Women's and Children's Hospital Research Centre, Adelaide, South Australia, Australia.
²⁴ Biostatistics Unit, South Australian Health and Medical Research Institute, Adelaide, South Australia, Australia.
²⁵ Unity Health, Toronto, Ontario, Canada.
²⁶ Temerty Centre for Artificial Intelligence Research and Education in Medicine (T-CAIREM), University of Toronto, Toronto, Ontario, Canada.
²⁷ Seattle Children's Hospital, Seattle, WA, USA.
²⁸ School of Public Health, University of Adelaide, Adelaide, South Australia, Australia.
²⁹ Cropify, Adelaide, South Australia, Australia.
³⁰ Google Research, Mountain View, CA, USA.
³¹ Division of Urology, Department of Surgery, The Hospital for Sick Children, Toronto, Ontario, Canada.
³² School of Psychology, University of Adelaide, Adelaide, South Australia, Australia.
³³ Division of Biomedical Informatics, Department of Medicine, University of California San Diego, San Diego, CA, USA.
³⁴ Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, UK.
³⁵ Queensland Digital Health Centre, University of Queensland, Brisbane, Queensland, Australia.
³⁶ School of Computing Technologies, RMIT University, Melbourne, VIC, Australia.
³⁷ Institute of Inflammation and Ageing, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK.
³⁸ University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK.
³⁹ National Institute for Health and Care Research, Birmingham Biomedical Research Centre, University of Birmingham, Birmingham, UK.

PMID: 39762426
DOI: 10.1038/s41591-024-03364-1

No abstract available

PubMed Disclaimer

Conflict of interest statement

Competing interests: S.R.P. is an employee of Google and may own stock as a part of a standard compensation package.

References

1. Wiens, J. et al. Nat. Med. 25, 1337–1340 (2019). - DOI - PubMed
1. Liu, X. et al. Lancet Digit. Health 2, e537–e548 (2020). - DOI - PubMed - PMC
1. Rivera, S. C. et al. Lancet Digit. Health 2, e549–e560 (2020). - DOI - PMC
1. Vasey, B. et al. BMJ 377, e070904 (2022). - DOI - PubMed - PMC
1. Fraser, A. G. et al. Expert Rev. Med. Devices 20, 467–491 (2023). - DOI - PubMed

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CANAIRI: the Collaboration for Translational Artificial Intelligence Trials in healthcare

Affiliations

CANAIRI: the Collaboration for Translational Artificial Intelligence Trials in healthcare

Authors

Affiliations

Conflict of interest statement

References

Publication types

LinkOut - more resources

Full Text Sources