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Multicenter Study
. 2024 Dec;44(6):400-411.
doi: 10.14639/0392-100X-N2973.

Factors influencing audiologic outcomes in ossiculoplasty for chronic otitis media: a prospective multicentre study

Gianluca Fadda  1 , Federico Merlino  2 , Giovanni Cavallo  1 , Simone Moglio  1 , Giuseppe Magliulo  3 , Giannicola Iannella  3 , Antonio Greco  3 , Annalisa Pace  3 , Andrea De Vito  4 , Giovanni Cammaroto  4 , Salvatore Ronsivalle  5 , Milena Di Luca  5 , Federica Parisi  6 , Antonio Frisina  7 , Pietro Canzi  8 , Salvatore Ferlito  6 , Antonino Maniaci  9
Affiliations
Multicenter Study

Factors influencing audiologic outcomes in ossiculoplasty for chronic otitis media: a prospective multicentre study

Gianluca Fadda et al. Acta Otorhinolaryngol Ital. 2024 Dec.

Abstract

Objectives: Chronic otitis media (COM) is a prevalent condition affecting auditory function. Ossiculoplasty is a known treatment strategy, but its effectiveness concerning the presence of cholesteatoma has not been extensively studied.

Methods: We conducted a multicentre study involving 153 patients diagnosed with COM without cholesteatoma (ncCOM) and with cholesteatoma (cCOM). Patients underwent ossiculoplasty, and postoperative hearing outcomes were analysed.

Results: After patient selection, 133 participants were included. Postoperatively, significant improvements in hearing function were observed in both groups, substantiating the role of ossiculoplasty in treatment of COM. However, different outcomes were noted between ncCOM and cCOM. Patients with cCOM demonstrated a slightly lesser degree of hearing improvement post-surgery compared to their ncCOM counterparts.

Conclusions: Our findings confirm ossiculoplasty as a standard and effective treatment strategy for COM. The presence of cholesteatoma may influence the effectiveness of surgery, underscoring the need for individualised surgical planning. Future research should focus on confirming these results and more comprehensively exploring the impact of cholesteatoma on surgical outcomes.

Keywords: cholesteatoma; chronic otitis media; ear surgery; hearing outcomes; ossiculoplasty.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Cover figure.
Cover figure.
Comprehensive analysis of surgical interventions and hearing outcomes in chronic otitis media (COM). Our graphical cover illustrates the impact of various surgical approaches on hearing outcomes in patients with different tympanic membrane conditions, comparing COM with and without cholesteatoma while analysing preoperative and postoperative air-bone gap (ABG) outcomes for non-cholesteatomatous (ncCOM) and cholesteatomatous (cCOM) cases. Our findings highlight significant differences in hearing improvement between these groups and describe the effectiveness of partial ossicular reconstruction prosthesis (PORP) and total ossicular reconstruction prosthesis (TORP) to address hearing loss across distinct middle ear pathologies, providing a comprehensive view of subgroup analysis.
Figure 1.
Figure 1.
Flow-diagram of the study protocol.
Figure 2.
Figure 2.
Evaluation of preoperative and postoperative outcomes for partial ossicular reconstruction prosthesis (PORP) versus total ossicular reconstruction prosthesis (TORP). The results demonstrate the effectiveness of both surgical approaches in addressing hearing loss in patients with distinct middle ear pathologies.
Figure 3.
Figure 3.
Analysis of preoperative and postoperative air-bone gap (ABG) outcomes for patients with non-cholesteatomatous (ncCOM) and cholesteatomatous chronic otitis media (cCOM). The data highlight significant differences in hearing improvement between the two groups.
Figure 4.
Figure 4.
Comparison of chronic otitis media (COM) with and without cholesteatoma. This figure illustrates the impact of surgical interventions of CWD vs CWU on hearing outcomes in patients with different tympanic membrane conditions.
See this image and copyright information in PMC

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