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Review
. 2024 Sep;38(3):233-245.
doi: 10.1016/j.bpa.2024.10.002. Epub 2024 Oct 9.

Navigating coagulopathy in obstetric hemorrhage: The role of point-of-care testing

Nicholas Gill  1 , Alexander Butwick  2 , Sarah F Bell  3
Affiliations
Review

Navigating coagulopathy in obstetric hemorrhage: The role of point-of-care testing

Nicholas Gill et al. Best Pract Res Clin Anaesthesiol. 2024 Sep.

Abstract

Postpartum hemorrhage (PPH) remains the leading cause of maternal mortality and morbidity worldwide. Recent advances in understanding the hemostatic changes of pregnancy and PPH have led to the development of obstetric-specific approaches to resuscitation. This article aims to examine. 1) changes in the coagulation system during pregnancy. 2) types of coagulopathy associated with PPH, and. 3) the role of point of care tests of coagulation in PPH.

Keywords: Fibrinogen concentrate; Obstetric coagulopathy; Postpartum hemorrhage; Tranexamic acid; Viscoelastic hemostatic assays.

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Conflict of interest statement

Declaration of competing interest SB has received lecture honorarium from Werfen and research support from Werfen, Haemonetics and CSL Behring. AB has received honoraria from Haemonetics. Corp. (Boston, Massachusetts) and Octapharma (Paramus, New Jersey). NG has no conflicts of interest to declare.

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