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. 2024 Dec 12;29(24):5859.
doi: 10.3390/molecules29245859.

Release and Disintegration Properties of Poly(lactic Acid) Films with Allyl Isothiocyanate-β-Cyclodextrin Inclusion Complexes for Active Food Packaging

Cristina Muñoz-Shugulí  1   2 , Francisco Rodríguez-Mercado  2 , Abel Guarda  2 , María José Galotto  2 , Alfonso Jiménez  3 , María Carmen Garrigós  3 , Marina Ramos  3
Affiliations

Release and Disintegration Properties of Poly(lactic Acid) Films with Allyl Isothiocyanate-β-Cyclodextrin Inclusion Complexes for Active Food Packaging

Cristina Muñoz-Shugulí et al. Molecules. .

Abstract

This study aimed to enhance the properties and compostability of active poly(lactic acid) (PLA) films by incorporating β-cyclodextrin (β-CD) inclusion complexes with allyl isothiocyanate (AITC). Films were prepared using melt extrusion and characterized based on their structural, chemical, morphological, thermal, and barrier properties. These inclusion complexes improved the thermal stability and moisture absorption of films, enhancing disintegration under composting conditions. The release of AITC in the vapor phase was responsive to relative humidity, maintaining the antimicrobial functionality at low values and releasing effectively at higher humidity levels, with a maximum release at 100%. Incorporating 5% and 10% β-CD:AITC complexes accelerated disintegration under composting conditions, reducing the time by 5 days for disintegration compared to pure PLA, achieving up to 90% in 23 days. These results, with a general improvement in functional properties, suggest that PLA films with β-CD:AITC are promising for developing sustainable, biodegradable antimicrobial packaging solutions for food applications.

Keywords: PLA; active food packaging; allyl isothiocyanate; disintegration; release; β-cyclodextrin.

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Conflict of interest statement

The authors declare no conflicts of interest.

Figures

Figure 1
Figure 1
(a) FESEM micrographs; (b) XRD diffractograms of extruded PLA (P0) and active films (P5 and P10).
Figure 2
Figure 2
Release of AITC from active films to headspace at 20 °C and under different RHs (25, 50 and 100% RH): (a) P5; (b) P10 active films.
Figure 3
Figure 3
Disintegration of PLA and active films under composting conditions (dotted red line represent the 90% of the disintegration test established by the UNE-EN 13432 normative). Columns with the same letter (a, b, c) within a day show statistical similarity between films (p > 0.05) according to ANOVA and Tukey tests.
Figure 4
Figure 4
FESEM surface micrographs of the films subjected to the disintegration process under composting conditions.
Figure 5
Figure 5
FTIR spectra of the films subjected to the disintegration process under composting conditions.
Figure 6
Figure 6
TGA and DTGA curves of the films subjected to the disintegration process under composting conditions.
Figure 7
Figure 7
DSC thermograms obtained during the first heating (left) and second heating (right) of the PLA (P0) and active (P5 and P10) films.
See this image and copyright information in PMC

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