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. 2024 Nov 21;13(12):1027.
doi: 10.3390/pathogens13121027.

Prevalence of Non-Viral Bloodborne Pathogens Among Healthy Blood Donors in Western Mexico: Problems and Failures of Public Health Policy

José de Jesús Guerrero-García  1   2 , Alejandra Flores-González  2 , Alma Marina Sánchez-Sánchez  3 , Rafael Magaña-Duarte  1 , Mario Alberto Mireles-Ramírez  4 , Pablo Cesar Ortiz-Lazareno  5 , Erick Sierra Díaz  6 , Daniel Ortuño-Sahagún  3
Affiliations

Prevalence of Non-Viral Bloodborne Pathogens Among Healthy Blood Donors in Western Mexico: Problems and Failures of Public Health Policy

José de Jesús Guerrero-García et al. Pathogens. .

Abstract

Background and objectives: Non-viral bloodborne diseases are a group of infections that are a public health problem worldwide. The incidence of diseases such as brucellosis and syphilis is increasing in the Americas and Europe. Chagas disease is an endemic problem in Latin America, the United States and Europe. This study aims to determine the prevalence of non-viral bloodborne diseases in blood donors and to discuss some issues related to federal regulations for the control and prevention of these infectious diseases in Mexico.

Material and methods: A cross-sectional study was conducted in the Western National Medical Center Blood Bank, including 228,328 blood donors (2018-2023). Frequencies, percentages, means, standard deviation and confidence intervals (CI) were calculated for demographic data. Prevalences were expressed as rates per 100,000 with 95% CI.

Results: Of 3949 seroreactive or undetermined blood donors at the first screening, a total of 682 (0.299%) completed their follow-up test and were positive for Treponema pallidum (478), Trypanosoma cruzi (83), or Brucella spp. (121). The overall prevalence for non-viral bloodborne diseases was 299 per 100,000 blood donors. The prevalence for syphilis, Chagas disease, and Brucella was 209, 36, and 53 per 100,000 respectively.

Conclusion: Federal regulations should be reviewed to formulate specific public health policies focused on controlling and preventing nonviral bloodborne diseases.

Keywords: Chagas disease; Mexico; blood donors; bloodborne pathogens; brucellosis; syphilis.

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Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as potential conflicts of interest.

Figures

Figure 1
Figure 1
Overview of screening, follow-up and confirmation of Syphilis, Chagas disease and brucellosis in blood donors.
Figure 2
Figure 2
Classification of positive cases of Syphilis, Chagas disease and brucellosis, according to blood donor classification.
See this image and copyright information in PMC

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References

    1. WHO . WHO Guidelines Approved by the Guidelines Review Committee. World Health Organization; Geneva, Switzerland: 2009. Screening Donated Blood for Transfusion-Transmissible Infections: Recommendations. - PubMed
    1. Guerrero-Garcia J.J., Zuniga-Magana A.G., Barrera-De Leon J.C., Magana-Duarte R., Ortuno-Sahagun D. Retrospective Study of the Seroprevalence of HIV, HCV, and HBV in Blood Donors at a Blood Bank of Western Mexico. Pathogen. 2021;10:878. doi: 10.3390/pathogens10070878. - DOI - PMC - PubMed
    1. Bloch E.M., Krause P.J., Tonnetti L. Preventing Transfusion-Transmitted Babesiosis. Pathogen. 2021;10:1176. doi: 10.3390/pathogens10091176. - DOI - PMC - PubMed
    1. Tonnetti L., Dodd R.Y., Foster G., Stramer S.L. Babesia blood testing: The first-year experience. Transfusion. 2022;62:135–142. doi: 10.1111/trf.16718. - DOI - PubMed
    1. Hochberg N.S., Montgomery S.P. Chagas Disease. Ann. Intern. Med. 2023;176:ITC17–ITC32. doi: 10.7326/AITC202302210. - DOI - PMC - PubMed

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