Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2025 Jan 6;13(1):e70086.
doi: 10.1002/ccr3.70086. eCollection 2025 Jan.

Vibrio cholerae Skin and Soft Tissue Infection Complicated by Sepsis in an Immunocompromised Patient: A Rare Case Report

Erin Rebecca Carr  1 , Adrian Estepa  2 , Jordan Colson  3 , Folusakin Ayoade  2
Affiliations

Vibrio cholerae Skin and Soft Tissue Infection Complicated by Sepsis in an Immunocompromised Patient: A Rare Case Report

Erin Rebecca Carr et al. Clin Case Rep. .

Abstract

Physicians should consider non-O1, non-O139 Vibrio cholerae (NOVC) in the differential diagnosis of cellulitis complicated by sepsis, especially in immunocompromised patients when potential exposure exists. Due to the pathogen's potential for severe infections and rising incidence from environmental changes, we emphasize the need for increased awareness and appropriate treatment guidelines.

Keywords: Vibrio cholerae; bacteremia; cellulitis; sepsis.

PubMed Disclaimer

Conflict of interest statement

The authors declare no conflicts of interest.

Figures

FIGURE 1
FIGURE 1
Left lateral calf with erythema, petechiae, and edema without bullae.
FIGURE 2
FIGURE 2
Left lateral calf with erythema, petechiae, and edema without bullae.
FIGURE 3
FIGURE 3
Gram stain showing curved Gram‐negative rods.
FIGURE 4
FIGURE 4
Blood agar (BAP) on the left demonstrating mucoid beta‐hemolytic colonies. Growth on MacConkey agar (MAC) on the right demonstrating lactose non‐fermenting isolate.
See this image and copyright information in PMC

References

    1. Maraki S., Christidou A., Anastasaki M., and Scoulica E., “Non‐O1, Non‐O139 Vibrio cholerae Bacteremic Skin and Soft Tissue Infections,” Infectious Diseases (London, England) 48, no. 3 (2016): 171–176, 10.3109/23744235.2015.1104720. - DOI - PubMed
    1. Baker‐Austin C., Oliver J. D., Alam M., et al., “ Vibrio Spp. Infections,” Nature Reviews. Disease Primers 4, no. 1 (2018): 8, 10.1038/s41572-018-0005-8. - DOI - PubMed
    1. Homsy P., Skogberg K., and Jahkola T., “Three Cases of Fulminant Cellulitis Caused by Non‐O1, Non‐O139 Vibrio cholerae in Southern Finland,” Infectious Diseases (London, England) 52, no. 7 (2020): 506–510, 10.1080/23744235.2020.1756399. - DOI - PubMed
    1. Shanley J., Kanj A., El Zein S., et al., “Non‐O1, Non‐O139 Vibrio cholerae Bacteremia in an Urban Academic Medical Center in the United States,” IDCases 15 (2019): e00527, 10.1016/j.idcr.2019.e00527. - DOI - PMC - PubMed
    1. Ummu S. F., Ding C. H., Wahab A. A., and Tzar M. N., “Bullous Cellulitis as an Extraordinary Manifestation of a Vibrio cholerae O1 Ogawa Infection,” Tropical Biomedicine 40, no. 2 (2023): 170–173, 10.47665/tb.40.2.007. - DOI - PubMed

LinkOut - more resources