Eyelid Spindle Cell Lipoma: Case Report and Review of Three Patients in Literature

Abstract

A 39-year-old woman presented a saucer-shaped mass in the left upper eyelid and underwent the extirpation at local anesthesia. Pathologically, collagen fibers, capillaries, small vessels, and CD34-positive spindle cells were dispersed among mature adipose tissues, indicative of spindle cell lipoma. Long-lasting cyst-like eyelid masses would be usually dermoid cysts, and spindle cell lipoma would be listed as a rare pathological diagnosis in differential diagnoses of cyst-like lesions in the upper and lower eyelid.

Keywords: CD34; eyelid; orbital bony edge; pathology; spindle cell lipoma.

FIGURE 1

Left upper eyelid saucer‐shaped mass with inhomogeneous content on T1‐weighted axial image (arrow, A) and T2‐weighted axial image (arrow, B) of magnetic resonance imaging. Left upper eyelid subcutaneous flat mass with 2 × 2.5 cm in size at surgery (C) and macroscopic view of the extirpated mass with size reference of no. 15 curved blade (D). Note incision line and area of the mass are marked on the skin at surgery by local anesthesia (C). Collagen fibers, capillaries and small vessels, and spindle cells in small number which are dispersed among mature adipose tissues with varying sizes (E in low magnification, F in high magnification). Spindle cells are positive for CD34, supporting the diagnosis of spindle cell lipoma. Bar = 1000 μm in E, 200 μm in (F and G).