Myelinated non-axonal neuronal elements in the feline olfactory bulb lack sites with a nodal structural differentiation

Abstract

Myelinated dendrites in the external plexiform layer (EPL) of the feline olfactory bulb and myelinated axons in the lateral olfactory tract (LOT), were examined by transmission electron microscopy. The results show that the non-axonal myelin sheaths are extremely thin and short and that the number of myelin lamellae does not increase with increasing dendritic diameter. In myelinated LOT axons the sheaths tend to be thicker and the myelin lamellar number increases with axon diameter. Domains with node-like structural characteristics are not encountered along myelinated dendrites, neither between successive myelin sheaths nor where single sheaths terminate. The partly myelinated neuronal perikarya, which occur in the EPL, also lack node-like domains. In contrast, typical nodes are easily found in myelinated LOT axons. In the periglomerular region dendrites and neuronal perikarya are surrounded by non-compacted glial sheets. It is concluded that myelination and node formation are relatively independent events and that morphogenetic glial-neuronal interactions may give different results in different parts of the same neuron.