A long-ignored skeletal tissue filled with oil

Affiliations

¹ Program in Craniofacial Biology, Department of Orofacial Sciences, Department of Anatomy, Institute for Human Genetics, Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California, San Francisco, San Francisco, CA, USA.

Comment

Viviana Hermosilla Aguayo et al. Science. 2025.

. 2025 Jan 10;387(6730):136-137.

doi: 10.1126/science.adu7943. Epub 2025 Jan 9.

¹ Program in Craniofacial Biology, Department of Orofacial Sciences, Department of Anatomy, Institute for Human Genetics, Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California, San Francisco, San Francisco, CA, USA.

Abstract

Lipid-rich cartilage points to nonmetabolic functions of lipid vacuoles in mammals.

Superstable lipid vacuoles endow cartilage with its shape and biomechanics.
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