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Review
. 2025 Feb:104:104354.
doi: 10.1016/j.ajp.2024.104354. Epub 2024 Dec 26.

Deep brain stimulation - A primer for psychiatrists

Lavanya P Sharma  1 , Uma Maheswari Ganesh  2 , Shyam Sundar Arumugham  3 , Dwarakanath Srinivas  4 , Ganesan Venkatasubramanian  3 , Yc Janardhan Reddy  3
Affiliations
Review

Deep brain stimulation - A primer for psychiatrists

Lavanya P Sharma et al. Asian J Psychiatr. 2025 Feb.

Abstract

Deep Brain Stimulation is a form of neurostimulation where electrical stimulation is delivered via intracranial electrodes over specific subcortical targets. It has been increasingly used as an alternative to ablative procedures for psychiatric disorders refractory to standard treatments. This review describes the common psychiatric indications for DBS, the current evidence base, putative mechanisms, and future directions.

Keywords: Deep brain stimulation; Psychosurgery; Refractory.

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Conflict of interest statement

Declaration of Competing Interest The authors declare the following financial interests/personal relationships which may be considered as potential competing interests: Dr Lavanya P Sharma reports financial support was provided by Wellcome Trust DBT India Alliance. Dr Shyam Sundar A reports a relationship with Wellcome Trust DBT India Alliance that includes: funding grants. If there are other authors, they declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

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