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. 2025 Jan 8;33(1):15-16.
doi: 10.1016/j.chom.2024.12.008.

Bugs take the sting out

Arren J Liu  1 , Jonathan B Lynch  2
Affiliations

Bugs take the sting out

Arren J Liu et al. Cell Host Microbe. .

Abstract

Jiang et al. investigate the role of the microbiota in postherpetic neuralgia (PHN), a chronic pain condition resulting from varicella-zoster virus reactivation. They identify microbiome alterations in PHN patients, linking microbes and pain sensitivity. The researchers identify butyrate-producing Roseburia intestinalis as a mediator of pain sensitivity along the "gut-brain axis."

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Conflict of interest statement

Declaration of interests The authors declare no competing interests.

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