Development of precision medicine approaches to advance clinical trials for autism and social behavior: A research imperative

Kelsie A Boulton^{1

2}, Adam J Guastella^{1

2}

Affiliations

¹ Clinic for Autism and Neurodevelopmental research, Brain and Mind Centre, Children's Hospital Westmead Clinical School, Faculty of Medicine and Health, University of Sydney, Sydney 2050, Australia.
² Child Neurodevelopment and Mental Health Team, Brain and Mind Centre, University of Sydney, Sydney 2050, Australia.

Comment

Kelsie A Boulton et al. Proc Natl Acad Sci U S A. 2025.

. 2025 Jan 7;122(1):e2424066122.

doi: 10.1073/pnas.2424066122. Epub 2024 Dec 30.

Kelsie A Boulton^{1

2}, Adam J Guastella^{1

2}

¹ Clinic for Autism and Neurodevelopmental research, Brain and Mind Centre, Children's Hospital Westmead Clinical School, Faculty of Medicine and Health, University of Sydney, Sydney 2050, Australia.
² Child Neurodevelopment and Mental Health Team, Brain and Mind Centre, University of Sydney, Sydney 2050, Australia.

No abstract available

Conflict of interest statement

Competing interests statement:The authors declare no competing interest.

Nebulized vasopressin penetrates CSF and improves social cognition without inducing aggression in a rhesus monkey model of autism.
Talbot CF, Oztan O, Simmons SMV, Trainor C, Ceniceros LC, Nguyen DKK, Del Rosso LA, Garner JP, Capitanio JP, Parker KJ. Talbot CF, et al. Proc Natl Acad Sci U S A. 2024 Dec 3;121(49):e2418635121. doi: 10.1073/pnas.2418635121. Epub 2024 Nov 25. Proc Natl Acad Sci U S A. 2024. PMID: 39585977 Free PMC article.

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