Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2025 Mar:133:25-34.
doi: 10.1016/j.ejim.2024.12.033. Epub 2025 Jan 9.

Chronic obstructive pulmonary disease: A narrative synthesis of its hallmarks for palliative care clinicians

Affiliations
Review

Chronic obstructive pulmonary disease: A narrative synthesis of its hallmarks for palliative care clinicians

Jacopo D'Andria Ursoleo et al. Eur J Intern Med. 2025 Mar.

Abstract

Chronic obstructive pulmonary disease (COPD) is a life-limiting condition and the third leading cause of death worldwide. People with COPD experience physical and psychological symptoms and functional limitations that impair their quality of life. Their caregivers face adverse clinical outcomes due to personal, social, and financial demands. As such, recent emphasis has been placed on early referral to palliative care services to enhance prognostic awareness, clarify goals of care, and manage symptoms. In this narrative synthesis of key aspects of COPD care, we propose practical, evidence-based strategies to integrate palliative care principles with conventional disease-directed treatments throughout the illness trajectory. We emphasize the importance of equipping clinicians caring for people with COPD with a thorough understanding of both the inherent disease complexities and the cornerstones of its multimodal management, including palliative care, to address the unique psychosocial and physical needs of this patient population.

Keywords: COPD; Chronic obstructive pulmonary disease; Dyspnea; End of life; Palliative care; Symptom management.

PubMed Disclaimer

Conflict of interest statement

Declaration of competing interest The other authors declare that they have no competing interests.

Figures

Fig. 1.
Fig. 1.. The hallmarks of COPD for palliative care clinicians caring for people with COPD.
Visualization of the narrative review including background, its conclusions, and the featured hallmarks of chronic obstructive pulmonary disease (COPD), alongside practical tips for palliative care clinicians caring for these patients. COPD: chronic obstructive pulmonary disease; PC: palliative care; ACP: advanced care planning.
Fig. 2.
Fig. 2.. The multidimensional nature of chronic obstructive pulmonary disease (COPD)-related suffering.
The diagram underscores the complex interplay between the spiritual, physical, psychological, and social dimensions of distress experienced by people with COPD.
Fig. 3.
Fig. 3.. Dyspnea management for people with COPD.
Comprehensive overview of evidence-based interventions for the management of dyspnea in people with COPD. Pharmacological and non-pharmacological interventions should be integrated to effectively alleviate this debilitating symptom.

References

    1. Christenson SA, Smith BM, Bafadhel M, Putcha N. Chronic obstructive pulmonary disease. The lancet. Elsevier B.V.; 2022. p. 2227–42. - PubMed
    1. Agustí A, Celli BR, Criner GJ, et al. Global initiative for chronic obstructive lung disease 2023 report: GOLD executive summary. Eur Respiratory J 2023;61:2300239. - PMC - PubMed
    1. Vogelmeier CF, Criner GJ, Martinez FJ, et al. Global strategy for the diagnosis, management, and prevention of chronic obstructive lung disease 2017 report. GOLD executive summary. Am J Respir Crit Care Med 2017;195:557–82. - PubMed
    1. Suen AO, Cenzer I, Iyer AS, Witt LJ, Smith AK, Kotwal A. The national prevalence of supplemental oxygen use in persons with chronic obstructive pulmonary disease: a comparison of claims-based and self-reported supplemental oxygen use. Ann Am Thorac Soc 2024;21:838–40. - PMC - PubMed
    1. Baltaji S, Cheronis N, Bajwa O, Cheema T. The role of palliative care in COPD. Crit Care Nurs Q 2021;44:113–20. Lippincott Williams and Wilkins. - PubMed

MeSH terms