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. 2025 Jan 11;41(2):30.
doi: 10.1007/s11274-024-04240-3.

Genomic insights into Thermomonas hydrothermalis: potential applications in industrial biotechnology

Songül Yaşar Yıldız  1
Affiliations

Genomic insights into Thermomonas hydrothermalis: potential applications in industrial biotechnology

Songül Yaşar Yıldız. World J Microbiol Biotechnol. .

Abstract

Thermomonas hydrothermalis, a thermophilic bacterium isolated from hot springs, exhibits unique genomic features that underpin its adaptability to extreme environments and its potential in industrial biotechnology. In this study, we present a comparative genomic analysis of two strains, DSM 14834 and HOT.CON.106, revealing distinct metabolic pathways and stress response mechanisms. The genome annotation highlighted strain-specific variations, such as enhanced motility and chemotaxis capabilities in HOT.CON.106 and a stronger genomic stability emphasis in DSM 14834. Comparative analysis with other Thermomonas species demonstrated that T. hydrothermalis possesses a unique genomic architecture, including genes for thermostable enzymes (e.g., amylases and pullulanases) and secondary metabolite biosynthesis. These enzymes and metabolites have significant industrial potential in high-temperature processes such as bioenergy production, bioplastics synthesis, and bioremediation. The findings underscore the relative differentiation between the strains and their broader implications for sustainable biotechnology, offering a basis for further exploration of thermophilic microorganisms in industrial applications.

Keywords: Thermomonas hydrothermalis; Biotechnological potential; Genome analysis; Secondary metabolites; Thermophiles; Thermostable enzymes.

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Conflict of interest statement

Declarations. Competing interests: The authors declare no competing interests. Conflict of interest: The authors declare no competing interests. Ethical approval: This article does not include any studies with human or animal participants.

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