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Case Reports
. 1985 Mar;66(3):173-80.

Abnormal length of cilia as a possible cause of defective mucociliary clearance

B A Afzelius, G Gargani, C Romano
  • PMID: 3979484
Case Reports

Abnormal length of cilia as a possible cause of defective mucociliary clearance

B A Afzelius et al. Eur J Respir Dis. 1985 Mar.

Abstract

A 12-year-old girl with obstructive lung disease was examined with respect to the ultrastructure of her nasal mucociliate epithelium. She had the characteristics of the immotile-cilia syndrome: chronic rhinitis, sinusitis, and bronchitis, a severely decreased mucociliary clearance of the lungs, and nasal polyps. The nasal cilia showed a normal cross-sectional appearance but were found to have twice the normal length: 12 micron rather than 6 micron. We conclude that the patient represents a new subgroup of the immotile-cilia syndrome and that her cilia are unable to perform their normal tasks.

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